虚拟组织学血管内超声的研究现状和展望  

Current Status and Future Perspectives of Virtual Histology Intravascular Ultrasound*

作　　者：吴小凡[1] 柳弘[1] 吕树铮[1] 

机构地区：[1]首都医科大学附属北京安贞医院心内科,北京100029

出　　处：《心血管病学进展》2010年第6期788-790,共3页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(项目批准号:81000655)资助课题

摘　　要：冠状动脉斑块的形态和组成反映了动脉粥样硬化的发展进程。病理研究将斑块分为稳定性斑块和不稳定性斑块,后者以大的脂质核心覆盖薄纤维帽为特征,是斑块破裂继发血栓形成导致急性冠状动脉综合征,或内膜增生致介入术后再狭窄的重要原因之一。虚拟组织学血管内超声能够有效地在体评价斑块的组成和性质。本综述主要介绍虚拟组织学血管内超声在心血管疾病尤其是介入心脏病学领域的研究进展。Coronary arterial plaque morphology and composition indicate the progress of atherosclerosis.According to the pathological studies,coronary plaque can be divided into two groups—stable plaque without progression of stenosis and unstable plaque with progression of stenosis followed by acute coronary syndrome.The features of the latter are the presence of a large lipid core with a thin fibrous cap,which causes plaque rupture and/or thrombus followed by rapid progression,or intimal hyperplasia,which causes a gradual progressive condition,such as restenosis after percutaneous coronary intervention.Virtual histology intravascular ultrasound（VH-IVUS） is used to assess in vivo the characteristics of coronary plaque.The present article focuses on the progress of VH-IVUS in relation to its use in identifying atherosclerosis.

关 键 词：虚拟组织学 血管内超声 介入心脏病学 

分 类 号：R541.4[医药卫生—心血管疾病]