绝经后女性2型糖尿病患者雌激素水平与胰岛素抵抗、血脂、血压的关系  

Relationship between Estrogen Levels and Insulin Resistance,Blood Lipids,and Blood Pressure in Postmenopausal Women with Type 2 Diabetes

作　　者：李广红[1] 刘丽[1] 刘媛媛[1] 朱栗文[1] 

机构地区：[1]吉林大学第一医院内分泌科,长春130021

出　　处：《医学综述》2010年第21期3315-3317,共3页Medical Recapitulate

摘　　要：女性绝经后,随着雌激素水平降低,胰岛素抵抗(IR)、2型糖尿病、高脂血症、高血压等代谢疾病的发病率也随之逐渐升高,且互相作用,影响女性健康。研究显示雌激素减少与IR有关,而IR是各种代谢疾病的主线。雌激素替代能增强胰岛素的敏感性,改善糖、脂代谢紊乱,缓解IR,防止IR综合征的发生,但雌激素替代治疗的利与弊及合理使用有待于进一步研究。现对绝经后女性2型糖尿病患者雌激素水平与胰岛素抵抗、血脂、血压的关系予以综述。As the decline of estrogen in postmenopausal women,insulin resistance（ IR） can occur,and type 2 diabetes,hyperlipidemia,high blood pressure,the incidence of metabolic diseases also will gradually rise,meanwhile they influence each other,affecting the health of women. Study shows that reduction of estrogen has related to IR,and the IR is the main line of various metabolic diseases,estrogen replacement can enhance insulin sensitivity,improve glucose and lipid metabolism disorders,alleviate insulin resistance and prevent the occurrence of insulin resistance syndrome. However,the advantages and disadvantages of estrogen replacement therapy and the rational uses need to be further research. This article reviewed the relationship between estrogen levels and insulin resistance,blood lipids,and blood pressure in postmenopausal women with type 2 diabetes.

关 键 词：绝经后女性2型糖尿病 雌激素 胰岛素抵抗 血脂 血压 

分 类 号：R587.1[医药卫生—内分泌]