皮下注射低分子肝素局部压迫时间的探讨  

After the subcutaneous injection of low-molecular-weight heparin (LMWH) to explore the local pressing time.

作　　者：曾锐[1] 梁静[1] 

机构地区：[1]成都市第二人民医院内科,四川成都610017

出　　处：《四川医学》2010年第11期1721-1722,共2页Sichuan Medical Journal

摘　　要：目的探讨皮下注射低分子肝素局部压迫时间与皮下出血发生率及出血面积的关系,同时找出较为有效的压迫时间,以减少皮下出血的发生及减小出血面积。方法选择我科住院治疗不稳定性心绞痛及急性心肌梗死失去溶栓机会而行低分子肝素治疗的患者38例,将每例患者5次皮下注射分为5组,每组的压迫时间随机定为1min、2min、3min、4min、5min,12h后观察皮下出血的例次及出血面积的大小。结果局部不同压迫时间皮下出血率比较,3min组与1min、2min组间差异无统计学意义,P<0.05,与4min、5min组间差异无统计学意义。局部不同压迫时间中、重度皮下出血率3min组与1min、2min组间差异有统计学意义,P<0.05,与4min、5min组间差异无统计学意义。轻度皮下出血率比较,3min组与1min、2min组间差异无统计学意义,P>0.05,与其他相邻组间差异无统计学意义。结论皮下注射低分子肝素后局部压迫3min可以有效降低皮下出血率及较大面积出血率,对减轻患者紧张心理及疼痛有积极作用。Objective To explore the relationship among the local pressing time,the incidence and the size of subcutaneous hemorrhage,and find an optimum pressing time in order to reduce the incidence and the size of subcutaneous hemorrhage after the subcutaneous injection of low-molecular-weight heparin（LMWH）.MethodsThe 38 patients who were assigned to receive LMWH were divided into five groups（1,2,3,4 or 5 minutes） by random,the incidence and the size of subcutaneous hemorrhage were measured.ResultsThe incidence of subcutaneous hemorrhage and the occurrence of large size were significantly different among the 1-minute group,2-minute group and 3-minute group（P0.05）,while there were no difference among the 3-minute group,4-minute group and 5-minute group.Conclusion Pressing for five minutes can effectively reduce the incidence and the size of subcutaneous hemorrhage resulted from subcutaneous injection of LMWH.

关 键 词：皮下出血 皮下注射 低分子肝素 压迫时间 

分 类 号：R472[医药卫生—护理学]