2型糖尿病合并冠心病患者冠状动脉病变特点  

Characteristics of coronary angiography in type 2 diabetes mellitus with coronary heart disease

作　　者：陈文[1] 王又平[1] 王相智[1] 

机构地区：[1]徐州市第一人民医院心内科,江苏省221002

出　　处：《中华实用诊断与治疗杂志》2010年第11期1070-1071,1074,共3页Journal of Chinese Practical Diagnosis and Therapy

摘　　要：目的:观察2型糖尿病合并冠心病患者临床及冠状动脉病变特点。方法:经冠状动脉造影确诊的122例冠心病患者中合并2型糖尿病者62例为糖尿病组,无糖尿病者60例为对照组,比较2组临床表现、不同受累血管支数、尿微量白蛋白及左室射血分数。结果:糖尿病组高血压、高脂血症、无痛性心肌缺血、心力衰竭发生率高于对照组(P<0.05)。糖尿病组冠状动脉血管受累程度高且弥漫性血管病变较对照组多(P<0.01),左室射血分数低(P<0.05)。有微量白蛋白尿者冠状动脉血管病变及心功能损害更严重。结论:2型糖尿病可促进冠状动脉病变的发生及发展,是冠心病的独立致病因素。伴微量白蛋白尿的2型糖尿病合并冠心病患者冠状动脉病变更严重。Objective To study the clinical and angiographical characteristics of coronary heart disease in patients with type 2 diabetes mellitus.Methods A total of 122 cases of coronary heart disease proved by coronary angiography were divided into 62 cases complicated with type 2 diabetes mellitus（DM group） and 60 cases without type 2 diabetes mellitus（control group）.The two groups were compared the clinical manifestations,the number of involved coronary vessels,microalbuminuria and left ventricular ejection fraction.Results DM group had more cardiovascular risk factors as hypertension,hyperlipidemia,silent myocardial ischemia and heart failure.Compared with control group,DM group had greater extent of coronary vessel involvement and more diffuse vascular lesions and lower left ventricular ejection fraction.The patients with microalbuminuria had more severe coronary vessel lesion and cardiac function damage.Conclusion Type 2 diabetes mellitus is an independent risk factor for coronary heart disease,which facilitates the occurrence and development of coronary heart disease.The patients with coronary heart disease complicated with type 2 diabetes mellitus have more severe coronary artery lesion when having microalbuminuria.

关 键 词：冠心病 2型糖尿病 微量白蛋白尿 

分 类 号：R541.4[医药卫生—心血管疾病]