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作 者:张峻[1]
机构地区:[1]柳州市中医院泌尿外科,广西壮族自治区柳州市545001
出 处:《中国组织工程研究与临床康复》2010年第44期8288-8292,共5页Journal of Clinical Rehabilitative Tissue Engineering Research
摘 要:背景:肺部感染是肾移植后常见的并发症和主要的死亡原因。目的:对肾移植后肺部感染的特点、临床表现、诊断和治疗进行综合分析。方法:应用计算机检索Pubmed数据库1997/2010及万方数据库2001/2010有关肾移植后肺部感染特点、临床诊断及治疗的文章,英文检索词为"kidney transplantation,pulmonary infection",中文检索词为"肾移植,肺部感染"。排除重复性研究,最终21篇符合要求被选为参考文献。结果与结论:通过综合文献发现,肾移植后肺部感染的症状和临床经过与普通人的肺部感染不完全相同,临床症状往往不典型,可通过多种手段检测,需要调整免疫抑制剂及规范治疗。肾移植后肺部感染应防治结合,严格做到早诊断、早治疗、联合用药、足量、全程,根据患者机体状况和术后不同时期及时调整免疫抑制用药方案。BACKGROUND:Pulmonary infection is the common complication and main cause of death after renal transplantation.OBJECTIVE:To comprehensively analyze the characteristics, clinical manifestations, diagnosis and treatment of pulmonary infection after renal transplantation.METHODS:A computer-based database online search of PubMed Database was undertaken to identify articles of the characteristics, clinical diagnosis and treatment of pulmonary infection after renal transplantation published in English from 1997 to 2010 with keyr words of "kidney transplantation, pulmonary infection".Wanfang Database was searched for the same articles published from 2001 to 2010 in Chinese with the keyr words of "kidney transplantation, pulmonary infection".The repetitive study was excluded.Finally, 21 articles were included according to inclusion criteria.RESULTS AND CONCLUSION:The clinical symptoms of pulmonary infection in renal transplantation are not identical to that of the common man.The symptoms are not typical.They can be detected by various means, and need to adjust immunosuppressant and regulatory treatment.Pulmonary infection should be prevented and treated with early diagnosis and treatment, drug combination, sufficient dose and full course of treatment.The dose of immunosuppressive drug should be adjusted according to the patients' body condition and at various periods.
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