微粒皮漂浮与皮浆移植修复特重度烧伤患者创面的疗效对比  

Curative effects of transplantation of micro-skin floating versus skin pulping for patients with extremely severe burn

作　　者：张明珠 周桂芬[2] 董运凤[3] 齐长春 赵志伟[4] 郭振存 董俐坤[6] 李兴华 董来成 裴银辉[2] 

机构地区：[1]河北钢铁集团唐山钢铁有限责任公司医院烧伤科,河北省唐山市063020 [2]华北煤炭医学院,河北省唐山市063020 [3]唐山市工人医院烧伤科,河北省唐山市063020 [4]山西省烧伤救治中心,山西省太原市030000 [5]二五五部队医院烧伤科,河北省唐山市063020 [6]唐山市中心血站机采科,河北省唐山市063020

出　　处：《中国组织工程研究与临床康复》2010年第44期8335-8338,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：背景:采用微粒皮漂浮的方法行微粒皮移植已成为近30年来修复特重度烧伤创面经典术式,并取得了良好的临床疗效。然而,采用皮浆涂抹的方法行微粒皮移植也能取得较好的治疗效果,但对此两种疗效方法的对比尚无报道。目的:观察皮浆移植法行微粒皮移植的临床疗效,并与常规微粒皮漂浮移植法进行对比。方法:选取特重烧伤患者72例,采用自身对照的方法,每例患者选取较为对称、创面性质相同的2处Ⅲ度烧伤切痂创面进行对照。皮浆移植组采用皮浆涂抹的方法行微粒皮移植,微粒皮漂浮组采用微粒皮漂浮的方法行微粒皮移植。应用网格计数法统计微粒皮移植后3,4和5周末2组创面愈合率。结果与结论:移植后第3,4和5周末扩张比在12.5:1以下的2段,两组创面愈合率基本相近(P>0.05),提示微粒皮漂浮与皮浆移植均为治疗大面积深度烧伤的良好方法。扩张比在12.6:1以上的2段,微粒皮漂浮组明显优于皮浆移植组(P<0.05或P<0.01),表明当扩张比超过12.5:1的情况下,有必要选用微粒皮漂浮法行微粒皮移植。BACKGROUND：It has already become being close to the style restoring classical skill to adopt the method of floating to transplant tautologies micro-skin during the past 30 years, and has got the fine clinical curative effect.But by means of skin pulping auto-epithelium grafting has also got fairly good clinical effect.However, the effect of these two treatment methods of the comparative study has not been reported.OBJECTIVE：To observe the clinical effects of the skin pulping auto-epithelium grafting and do a compare of clinical effects with the routine skill of antilogous micro-skin floating transplantation.METHODS：A total of 72 severe burn patients were recruited.In each patient, 2 symmetrical spots of Ⅲ-degree burn post-escharectomy were selected and were divided equally into micro-skin floating group and skin pulping ones.The skin pulping group was transplanted by skin pulping, while the micro-skin floating group by floating.Wound healing rates of every section were analyzed at the end of 3, 4 and 5 weeks after micro-skin transplantation by grid counting.RESULTS AND CONCLUSION：The recovery rates of the first two sections with expansion ratio less than 12.5：1 were similar at the end of 3, 4 and 5 weeks after transplantation （P0.05）, but the ones of the later two sections （greater than 12.6：1） were different, and the micro-skin floating group were obviously better then the skin pulping one at the same times （P0.05 or P0.01）.Whether it was necessary to select the method of micro-skin floating depends on the condition that the expansion ratio was lager than 12.5：1.

关 键 词：微粒皮 皮浆 漂浮 Ⅲ度烧伤 创面愈合 疗效 组织移植 

分 类 号：R617[医药卫生—外科学]