青岛地区1205名汉族青少年骨龄调查  

Investigation of bone age in 1205 Han adolescents from Qingdao city

作　　者：田晓青[1] 祖玉良 梁少华[1] 刘丰春[1] 

机构地区：[1]青岛大学医学院人体解剖学教研室,山东省青岛市266071 [2]青岛市骨伤科医院影像科,山东省青岛市266021

出　　处：《中国组织工程研究与临床康复》2010年第41期7761-7764,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：背景:骨龄为人类生长发育的重要参考指标,国内现引用的数据多为20世纪60年代的统计结果,而对现代青少年骨龄的研究较少。目的:了解青岛地区汉族青少年膝部和踝部长骨发育状况,探讨骨骺融合的变化趋势,为该地区新的青少年骨龄评价标准积累资料。方法:随机选择青岛地区9～20岁健康汉族青少年1205名,拍摄膝部和踝部正位片,统计各长骨干骺融合时间和女生月经初潮情况,并将长骨干骺融合时间与女生月经初潮情况进行相关分析。结果与结论:膝部及踝部长骨干骺融合时间顺序为:胫骨下端(男生:15.179岁,女生:13.379岁)、腓骨下端(男生:15.290岁,女生:13.472岁)、股骨下端(男生:15.629岁,女生:13.722岁)、腓骨上端(男生:15.708岁,女生:13.753岁)、胫骨上端(男16.329岁,女生:14.027岁)。干骺融合时间男生明显晚于女生。女生月经初潮时间与干骺融合时间成高度正相关。结果表明青岛地区汉族青少年的骨发育有明显提前趋势,因此有必要制定新的反映青少年骨发育水平的骨龄标准。BACKGROUND： Bone age is an important reference of growth and development of human race. The data referred to in China was studied in early 1960s, there are few studies concerning modern adolescents. OBJECTIVE： To assess the long bones’ development in knee and ankle joints of adolescents in Qingdao region, and to investigate the tendency of their skeletal development, which can add new data for the new standard of bone age of adolescents. METHODS： Totally 1 205 healthy adolescents, aged 9-20 years, living in Qingdao region were randomly selected. Anterior-posterior radiograms of knees and ankles were obtained. The time of epiphysis-diaphysis fusion of the long bones were observed. Meanwhile the correlation between the menarche and the epiphysis-diaphysis fusion time were analyzed. RESULTS AND CONCLUSION： The sequence of the epiphysis-diaphysis fusion in the knee and ankle long bones was as follow： the inferior end of tibia （Male： 15.179 years; Female： 13.379 years）, the inferior end of fibula （Male： 15.290 years; Female： 13.472 years）, the inferior end of femur （Male： 15.629 years; Female： 13.722 years）, the superior end of fibula （Male： 15.708 years; Female： 13.753 years）, and the superior end of tibia （Male： 16.329 years; Female： 14.027 years）. The females’ menarche was obviously advanced and was highly correlated with the epiphysis-diaphysis time. The bone age of adolescents in Qingdao region is obvious earlier than the old data. New data should be accumulated for the research of anthropology, clinical and forensic medicine.

关 键 词：骨龄 青少年 干骺融合 月经初潮 生长发育 青岛 

分 类 号：R318[医药卫生—生物医学工程]