异丙托溴铵溶液雾化吸入佐治新生儿感染性肺炎疗效观察  

Effect of pratropine aerosol inhalation on infectious pneumonia in newborns

作　　者：石润海[1] 卓志强[1] 陈宝川[1] 

机构地区：[1]福建省泉州市儿童医院,福建泉州362000

出　　处：《海南医学院学报》2010年第11期1430-1432,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020100394)~~

摘　　要：目的:观察吸入异丙托溴铵溶液及硫酸沙丁胺醇佐治新生儿感染性肺炎疗效。方法:将168例新生儿感染性肺炎患儿,随机分为两组,治疗组79例,对照组89例,治疗组应用0.5%硫酸沙丁胺醇每次0.25mL和0.025%异丙托溴铵每次0.5mL加生理盐水至2～3mL,空气压缩泵雾化吸入,每日2次,每次10～15min,疗程5～7d。对照组只用0.5%硫酸沙丁胺醇每次0.25mL加生理盐水至2～3mL,空气压缩泵雾化吸入,每日2次,每次5～10min,疗程5～7d。结果:总有效率治疗组88.6%(70/79),对照组73.0%(65/89)。治疗组有效率明显高于对照组(P<0.01)。结论:异丙托溴铵和硫酸沙丁胺醇联合雾化吸入,具有很大的支气管舒张效果。为新生儿感染性肺炎的辅助治疗提供了一个新的途径。Objective： To explore the effect of aerosol inhalation of pratropine and salbutamol sul fate on infectious pneumonia in newborns. Methods： A total of 168 newborns with infectious pneumonia were randomly divided into treatment group （79 cases） and control group （89 eases）. Patients in treatment group received aerosol inhalation of 2-3 mL solution for 10-15 min, including 0.25 mL 0.5% salbutamol sulfate, 0.5 mL 0. 025% pratropine and saline. The treatment was performed twice a day, and 5-7 d for a course. While cases in control group were treated by only aerosol inhalation of 0.25 mL 0.5 % salbutamol sulfate, 5-10 min every time, twice a day, and 5-7 d for a course. Results： The total efficacy was significantly higher in treatment group （88.6%, 70/79） than that in control group （73.0%, 65/89） （P〈0. 01）. Conclusions： The aerosol inhalation of pratropine and salbutamol sulfate is effective on dilating bronchus, and provides a new treatment for newborn infectious pneumonia.

关 键 词：异丙托溴铵溶液 空气压缩泵 雾化吸入 感染性肺炎 新生儿 

分 类 号：R563.1[医药卫生—呼吸系统]