不同年龄妇女孕酮水平与血脂变化的关系研究  

A study of the relationship between levels of progesterone and blood lipid in different age women

作　　者：方义[1] 韩秀晶[1] 郑君德[1] 李宁[1] 肖洪广[1] 

机构地区：[1]广州医学院第一附属医院检验科,广州510120

出　　处：《广州医药》2010年第6期49-51,共3页Guangzhou Medical Journal

摘　　要：目的探讨不同年龄妇女孕酮水平与血脂变化的关系。方法收集本院200例临床病例,按年龄分为育龄组、中年组及老年组,检测其血清孕酮、血脂的浓度并分析。结果总胆固醇在各组间均无统计学意义(P>0.05);甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、孕酮在育龄组与中年组间比较均无统计学意义(P>0.05),而老年组与育龄组、中年组间比较均有统计学意义(P<0.01)。结论老年妇女孕酮较中年及育龄妇女孕酮明显降低,同时伴TG、LDL-C升高,HDL-C降低,雌性激素孕酮水平变化与血脂代谢异常有关。Objective To study of the relationship between levels of progesterone and blood lipid in different age women.Methods To compare of blood serum progesterone and serum lipids concentration changes in Women of childbearing age group,middle-age group and elderly group. Results Serum total cholesterol concentration among the 3 groups had no significant difference（P 0.05）;Triglyceride concentration of childbearing age group and middle-aged group showed no significant difference（P 0.05）;Older women group with the rest of the two groups was significant difference（P 0.01）;High density lipoprotein cholesterol,low-density lipoprotein cholesterol in women of childbearing age group and among the middle-aged group has no significant differences in the results（P 0.05）;Older women group with the rest of the two groups was statistics difference（P0.05）;Serum progesterone of youth group and middle-aged group showed no significant difference,（P0.05）;older women group with the rest of the two groups was significantly different（P0.01）.Conclusion Older women hormone progesterone were significantly lower than the others.Older women with TG,LDL-CH increased,and HDL-CH decreased.This is relative to the blood lipid metabolic disorder caused by the change of levels of the female hormone progesterone.

关 键 词：甘油三酯 高密度脂蛋白 低密度脂蛋白 孕酮 

分 类 号：R543.5[医药卫生—心血管疾病]