棘球蚴逃避或抑制宿主免疫系统清除作用的机制研究进展  

Research progress in the mechanism of Echinococcus evasion

作　　者：李红卫[1] 杨玉荣[1] 

机构地区：[1]宁夏医科大学病原生物学教研室,银川750004

出　　处：《免疫学杂志》2010年第11期1000-1002,共3页Immunological Journal

基　　金：自然科学基金项目(30960339)

摘　　要：棘球属绦虫的生活史包括两个阶段。续绦期幼虫通常是单房内含液体的囊,有时多个房。囊外有宿主的纤维组织包绕,囊壁有两层,外层是坚硬且可变有弹性的薄片层,内层是生发层或有核层。棘球蚴依靠有效的逃避机制植入宿主,并能长期存活。我们进一步研究这些机制,为预防和治疗包虫病提供了方法和依据。The life cycle of Echinococcus spp involve two phages.The metacestode stage is a fluid-filled bladder usually unilocular but communicating chambers also occur.The cyst consists of an inner germinal or nucleated layer supported externally by a tough,elastic,acellular laminated layer of variable thickness,which is surrounded by a host-produced fibrous adventitial layer.The success of host colonization by Echinococcus depends on effective mechanisms of evasion.And Echinococcus can survive in the host for extended periods.This paper reviews recent progress in the mechanisms of Echinococcus evasion,which may offer methods and bases for therapeutic and preventive agents.

关 键 词：棘球蚴 逃避机制 

分 类 号：R383.3[医药卫生—医学寄生虫学]