MSCT评价冠状动脉狭窄程度与左心结构和功能的相关性  

Correlation between the severity of coronary artery stenosis,left ventricle anatomy and systolic function evaluated with multi-slice spiral CT

作　　者：曹阿丹[1] 牛玉军[1] 刘宁[1] 雷震[1] 张占锋[2] 赵学凯[1] 

机构地区：[1]辽宁医学院附属第一医院影像中心CT室,辽宁锦州121001 [2]辽宁医学院附属第一医院心内科,辽宁锦州121001

出　　处：《中国医学影像技术》2010年第11期2095-2098,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨MSCT无创性评价冠状动脉狭窄程度与左心结构和收缩功能的相关性。方法对200例拟诊为冠心病患者进行MSCT冠状动脉血管造影(MSCTCA),依美国心脏学会冠状动脉17段分段法,对各支狭窄节段进行Gensini积分(GS)评估,并利用MSCTCA原始数据一站式评估左心结构、功能参数及GS与左心结构和功能的相关性。结果将GS四分位分组,患者的LVDD、LADD、LVEDV、LVESV、MM、LVEF和FS在不同积分间差异有统计学意义(P<0.05),SV、CO差异无统计学意义(P>0.05)。GS与LVEF和FS呈线性负相关(P<0.05),与LVDD、LADD、LVEDV、LVESV、MM呈线性正相关(P<0.05),与SV和CO无相关性(P>0.05)。结论冠状动脉愈狭窄,心功能愈差。冠状动脉狭窄是造成左心室收缩功能减低和心肌重塑的一个重要原因。Objective To observe the correlation between severity of coronary artery stenosis,left ventricle anatomy and systolic function evaluated with MSCT.Methods Two hundred patients with suspected coronary heart disease（CHD）underwent MSCT coronary artery angiography（MSCTCA）.According to 17-segment modified American Heart Association classification,the stenosis of each branch segment was assessed with Gensini＇s score（GS）.The raw data of MSCTCA,parameters of left ventricular structure and function,as well as the relationship among them were evaluated only in a one-stop manner.Results GS was grouped according to quartile values.There were significant differences in left ventricular end diastolic dimension（LVDD）,left atrium end-diastolic dimension（LADD）,left ventricular end-diastolic volume（LVEDV）,left ventricular end-systolic volume（LVESV）,myocardial mass（MM）,left ventricular ejection fraction（LVEF）and fraction shortening（FS）（P0.05）,but differences in stroke volume（SV）,cardiac output（CO）were no significant（P0.05）.GS was positively correlated with LVDD,LADD,LVEDV,LVESV and MM,but negatively correlated with LVEF and FS（P0.05）,and was no significantly correlated with SV and CO（P0.05）.Conclusion The more the stenosis coronary artery,the worse the left ventricle systolic function.Coronary artery stenosis is an important cause of left ventricular systolic dysfunction and cardiac remodeling.

关 键 词：体层摄影术 X线计算机 心室功能 左 冠状血管狭窄 

分 类 号：R541.4[医药卫生—心血管疾病] R814.42[医药卫生—内科学]