3.0T磁共振动态增强扫描对富血供肝肿瘤的诊断价值  

Application of dynamic contrast-enhanced MRI in the diagnosis of hyper-vascular neoplasms of the liver

作　　者：郭卫华[1] 李传福[2] 尉从新[2] 侯金文[2] 

机构地区：[1]山东大学第二医院放射科,济南250033 [2]山东大学齐鲁医院放射科,济南250012

出　　处：《山东大学学报（医学版）》2010年第10期88-91,共4页Journal of Shandong University:Health Sciences

摘　　要：目的探讨3.0T磁共振动态增强扫描对富血供肝肿瘤的鉴别诊断价值。方法对40例富血供肝肿瘤(肝细胞癌26例,海绵状血管瘤12例,富血供转移瘤2例)相继进行MR平扫及3D FAME序列多期动态增强扫描,包括肝动脉期、门静脉期、平衡期及延迟期,观察病灶各期的强化特征。并利用动态强化自动分析软件及时间-信号强度曲线分析各种病变的曲线类型。结果富血供肝细胞癌的时间-信号强度曲线分为两种类型:Ⅰ型(速升速降)、Ⅱ型(速升缓降)。26例肝细胞癌中69%(18/26)表现为Ⅰ型曲线类型,31%(8/26)表现Ⅱ型曲线类型。肝血管瘤的动态增强曲线分为两种类型:Ⅰ型(缓升平坦型)、Ⅱ型(速升平坦型)。12例血管瘤中67%(8/12)表现为Ⅰ型曲线类型,33%(4/12)表现Ⅱ型曲线类型。2例富血供转移瘤表现为早期周边环状强化。结论 3.0T磁共振动态增强扫描有助于富血供肝肿瘤的诊断及鉴别诊断。Objective To evaluate the usefulness of three-dimensional fast acquisition plus multiphase enhanced fast GRE（3D FAME） sequence at 3.0T MR in diagnosing hyper-vascular neoplasms of the liver.Methods MR imaging was performed on 40 patients with hepatic neoplasms,including 26 hepatocellular carcinoma,12 hemangioma and 2 metastases.The imaging protocol consisted of a conventional plain scan and 3D FAME multi-phase dynamic scan（hepatic arterial,portal venous,equilibrium and delayed phases）.Enhancement patterns were observed and the time-signal intensity curve（TIC） was analyzed.Results There were characteristic enhancement patterns identified among various types of hyper-vascular liver masses.The time-signal intensity curve reflected the hemodynamic changes of the lesions.TIC of hepatocellular carcinoma was classified as： a） type Ⅰ： sharp incline and decline,which was seen in 69%（18/26） of cases;and b） type Ⅱ ： sharp incline with flat decline,which was seen in 31%（8/26）of cases.TIC of hemangioma was classified as： a） type Ⅰ： flat incline and plateau,which was seen in 67%（8/12）of cases;b） type Ⅱ ： sharp incline and plateau,which was seen in 33%（4/12） of cases.Two hyper-vascular metastases cases showed early peripheral-rim enhancement.Conclusion 3.0 T dynamic contrast-enhanced MRI is very helpful in diagnosing different hyper-vascular neoplasms of the liver.

关 键 词：肝肿瘤 磁共振成像 动态增强 

分 类 号：R455.2[医药卫生—运动医学]