启神胶囊治疗血管性痴呆的临床疗效初步观察  

Clinical study of the Qishen Capsule(启神胶囊) on the treatment effect in vascular dementia

作　　者：孙文燕[1] 傅仁杰[2] 孙建宁[1] 

机构地区：[1]北京中医药大学中药学院中药药理系,北京100102 [2]中日友好医院,北京100029

出　　处：《中药药理与临床》2010年第5期141-142,共2页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：目的:观察启神胶囊对血管性痴呆(VD)患者智能量表积分、中医症状及日常生活能力的影响,对其疗效进行客观评价。方法:采用DSM-IV VD诊断标准,结合中医辨证及Hachinski缺血量表(HIS)、长谷川痴呆量表(HDS)、简易精神状态检查量表(MMSE)、日常生活能力量表(ADL)的积分,选择35例血管性痴呆患者,以喜德镇作为阳性对照药,观察启神胶囊的疗效。结果:启神胶囊可显著提高VD患者不同痴呆量表的积分,显著改善中医痴呆症状,提高日常生活能力,治疗组总有效率为68.42%。结论:启神胶囊在改善VD患者智能障碍、日常生活能力等方面疗效肯定。Objective： To study the effect of Qishen Capsule on the scores of intelligence scale,TCM symptoms and activity of daily living.Methods： 35 patients with VD were randomly divided into 2 groups,namely,Qishen Capsule treating group and hydergine control group.The results were assessed mainly according to DSM-IV VD diagnostic standard,Hachinski Ischemic Score（HIS）,Hasegawa’s Dementia Scale（HDS）,Mini-Mental State Examination（MMSE） and Activity of Daily Living Scale（ADL）.Results： The scores of HDS,MMSE and ADL were significantly improved in both groups.Total effective rate was 68.42% in treating grorp,and 56.25% in control group.Conclusion： These results indicated that Qishen Capsule can improve the ability of learning and memory,also alleviate daily living activities in patients with VD.

关 键 词：启神胶囊 血管性痴呆 临床观察 

分 类 号：R277.7[医药卫生—中医学]