儿童肥胖症胰岛素抵抗的初步探讨  

The Preliminary Study on Insulin resistant of Childhood Obesity.

作　　者：毕旭明[1] 孙梅[1] 王永平[1] 宋淑英[1] 李长贤[1] 

机构地区：[1]山东省德州市人民医院儿科,253014

出　　处：《中国儿童保健杂志》1999年第2期100-101,共2页Chinese Journal of Child Health Care

摘　　要：目的　从免疫与糖代谢的关系方面探讨儿童肥胖症的发病机制。　方法　对５２ 例肥胖儿童及４０例正常儿童进行血糖、胰岛素、抗胰岛素抗体水平及葡萄糖耐量试验的检测对比分析。　结果　肥胖组血胰岛素水平和抗胰岛素抗体水平与对照组比较差异有非常显著意义（ Ｐ＜ ０ ．０１） ；肥胖儿童葡萄糖耐量试验呈延迟反应。　结论　肥胖儿童的胰岛素抵抗与抗胰岛素抗体水平有关。Objective To study the pathogenesis of obese children on the relationship between immunology and glucose metabolism. Methods The 52 obese children and 40 healthy children as control were determined to have contrast and analysis on glucose,insulin,antibody against insulin in blood and the glucose tolerance test. Resuts There were obvious difference in the concentration of insulin,antibody against insulin between obese group and control group ( P <0.01).The reaction of glucose tolerance test in obese children was delayed. Conclusion The insulin resistant of obese children was related to the level of antibody against insulin.

关 键 词：肥胖症 胰岛素抵抗 儿童 

分 类 号：R725.892[医药卫生—儿科]