心肌纵向应变与应变率对胎儿心脏功能的评估  

Longitudinal Cardiac Strain and Strain Rate for Evaluation of Fetal Cardiac Function

作　　者：夏珣[1] 李胜利[1] 余艳红[2] 王晨虹[3] 刘慧文 陈秀兰[1] 文华轩[1] 

机构地区：[1]南方医科大学附属深圳市妇幼保健院超声科,广东省深圳市518028 [2]南方医院妇产科 [3]南方医科大学附属深圳市妇幼保健院妇产科,广东省深圳市518028

出　　处：《中国超声医学杂志》2010年第11期1028-1030,共3页Chinese Journal of Ultrasound in Medicine

基　　金：国家科技支撑计划(No.2006BAI05A04)

摘　　要：目的探讨胎儿心肌纵向应变与应变率在评估胎儿心脏功能中的应用。方法通过Syngo US Workplace VVI工作站处理标准胎儿四腔心动态图(145例),分别获得左心室游离壁、室间隔、右心室游离壁的纵向应变、应变率、收缩期和舒张期速度测值并进行分析。结果 (1)左室心肌速度大小由室壁基底段向心尖段逐渐递减,应变-时间、应变率-时间曲线随节段的变化而保持稳定;(2)左心室游离壁、右心室游离壁、室间隔之间的应变、应变率、收缩期和舒张期速度均无显著性差异(P>0.05);(3)左心室、室间隔、右心室游离壁收缩期和舒张期心肌速度与孕周均呈正相关(P<0.05);(4)左心室、室间隔、右心室的心肌应变率和胎心率均呈正相关(P<0.05)。结论应用VVI检测应变和应变率可用于分析胎儿局部纵向心室壁运动,以及评估胎儿心脏功能。Objective To investigate the application of strain and strain rate in evaluating myocardial mechanics in fetal heart. Methods Two-dimensional 4-chamber images of the heart（n=145）were analyzed offline using Syngo US Workplace VVI software. Learning curves of velocity, strain, and strain rate and velocity vector images were performed. Longitudinal strain, strain rate,and diastolic and systolic velocity were measured in left ventricular free wall, ventricular septum, and right ventricular free wall. Results （1） Images from 145 cases were successfully analyzed. Learning curve showed that the velocity decreased from the base to the apex and that the strain and strain rate remained stable. （2）Strain, strain rate,and diastolic and systolic velocity had no significant difference in the left ventricular free wall, ventricular septum, and right ventricular free wall. （3）There was significant positive correlation between velocity and the gestational age（P^0.05）. （4）The strain rate had significant positive correlation with fetal heart rate（P〈0.05）. Conclusions Measurement of cardiac strain and strain rate using VVI can evaluate segmental ventricular motion and function.

关 键 词：胎儿心脏 应变 应变率 速度向量成像 超声 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]