Bacteriorhodopsin and SWCNT Scaffold for Optical Nanobiosensor  

作　　者：Aiswarya Radhakrishna Pillai Balraj Arunachalam Manish Shinde Rabinder Henry 

机构地区：[1]School of Interdisciplinary Science ＆ Technology, International Institute of lnformation Technology, Pune 411057, India [2]Centre for Materials for Electronics Technology, Panchawati, Pune 411008, India

出　　处：《Journal of Life Sciences》2010年第6期60-64,共5页生命科学（英文版）

摘　　要：This paper describes theoretical steps to develop an optical nanobiosensor using bacteriorhodopsin （BR） as the biomembrane and Single-Walled Carbon NanoTube （SWCNT） as the scaffold. Bacteriorhodopsin is a retinal protein used by archaea that come under the family of halobacteria. This retinal protein acts as a proton pump and resulting proton gradient is used to change the voltage that pass across the drain and source. The biosensor contains nano ISFET where the channel is made of a carbon nanotube for the conduction of current. The gate is replaced by bacteriorhodopsin biomembrane. Bacteriorhodopsin can be used as a molecular-level ultra fast bi-stable red / green photo switch for making 3D optical molecular memories that reliably store data with 10,000 molecules/bit. The molecules switch in femtoseconds. Biomembrane will sense 510 nm and 650 nm wavelength of light and the sensing voltage can be used to convert the data into digital signals. This molecular level memory device can be used for ‘Read-Write＇ operations. The sensor performance will also be ultra fast since it uses photons for the data storage, which are much faster than electrons used in normal memory devices, and the 3D storage capacity is much higher maximum of 10^13/cm^2.

关 键 词：Optical nanobiosensor BR HALOBACTERIA nano ISFET （Ion-Sensitive Field-Effect Transistor） archaea. 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] TB383[自动化与计算机技术—控制科学与工程]