润燥止痒胶囊联合羌月乳膏治疗单纯性女阴瘙痒症的疗效观察  

Observation of Effect of Runzao Itching Capsule Combined with Qiangyue Cream on Simple Vulva Pruritus

作　　者：屠丽娟[1] 孙卫国[1] 

机构地区：[1]南京医科大学附属淮安第一医院皮肤科,江苏淮安223300

出　　处：《中国现代应用药学》2010年第10期955-958,共4页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的观察润燥止痒胶囊联合羌月乳膏治疗单纯性女阴瘙痒症疗效。方法 80例分为两组,治疗组40例,口服润燥止痒胶囊4片.次-1,3次.d-1,同时外用羌月乳膏,涂患处,早晚各1次。对照组40例,口服咪唑斯汀10 mg.d-1,外用0.1%曲安奈德霜,早晚各1次。两组均连续治疗4周。结果治疗组有效率为62.50%,对照组有效率为65.00%,两组比较,无显著性差异(P>0.05)。两组治疗前后总积分差值治疗组为2.14±1.71,对照组为2.10±1.68,经统计学分析无显著性差异(P>0.05)。在治疗2周后治疗组的瘙痒积分为0.45±0.51,对照组瘙痒积分为0.82±0.77,有显著性差异;而在疗程结束时,治疗组的继发皮损积分为0.31±0.65,对照组的继发皮损积分为0.03±0.17,有显著性差异。结论润燥止痒胶囊联合羌月乳膏治疗单纯性女阴瘙痒症,疗效与口服咪唑斯汀加外用曲安奈德霜相近,但其止痒效果优于后者,对继发皮损改善逊于后者。OBJECTIVE To observe the effect of Runzao itching capsules combined with Qiangyue cream on simple vulva pruritus.METHODS Eighty cases were divided into two groups.Forty cases in treatment group took 4 Runzao itching capsules each time,thrice daily,and applied Qiangyue cream on affected part for external use twice a day.Forty cases in control group took 10 mg mizolastine once per day,and applied 0.1% triamcinolone acetonide cream twice a day in the morning and evening.Treatment lasted four weeks.RESULTS The rate of effectiveness in treatment group and control group were respectively 62.50% and 65%.There was no significant difference between the two groups（P〉0.05）.The total point difference before and past treatment of treatment group and control group were respectively 2.14±1.71 and 2.10±1.68.And there was no significant statistical difference（P〉0.05）.The itching point of treatment group and control group after two weeks’ treatment were respectively 0.45±0.51 and 0.82±0.77,and there was a statistical difference.At the end of the treatment,the secondary skin lesion point of treatment group was 0.31±0.65 and that of control group 0.03±0.17,and the points also showed statistical difference.CONCLUSION Rnuzao itching capsules combined with Qiangyue cream had the same effect on simple vulva pruritus as mizolastine with triamcinolone acetonide cream,but the effect of the former was better than that of the latter on stopping itching,and inferior on relieving secondary skin lesions.

关 键 词：女阴瘙痒症 润燥止痒胶囊 羌月乳膏 疗效 

分 类 号：R969.4[医药卫生—药理学] R984[医药卫生—药学]