舒芬太尼用于婴幼儿唇腭裂修复术的临床研究  

Clinical study of Sufentanil anesthesia to use in the babies and infants primary cleft of lip or palate repair

作　　者：成黎明[1] 曾焱[1] 李超[1] 

机构地区：[1]云南省昆明市儿童医院麻醉科,650034

出　　处：《中国医疗前沿》2010年第20期36-37,共2页China Healthcare Innovation

摘　　要：目的探讨舒芬太尼用于婴幼儿唇腭裂修复术的可行性。方法 60例婴幼儿唇腭裂修复术患儿随机分为两组:舒芬太尼组(Ⅰ组),芬太尼组(Ⅱ组),每组30例。Ⅰ组诱导方法:芬太尼4μg/kg,丙泊酚2mg/kg,维库溴铵0.1mg/kg。Ⅱ组诱导方法:舒芬太尼0.5μg/kg,丙泊酚2mg/kg,维库溴铵0.1mg/kg。插管后控制呼吸,麻醉维持间断追加维库溴铵,丙泊酚,芬太尼(Ⅰ组)或舒芬太尼(Ⅱ组),术中新鲜氧流量设定为2L/min,术中监测患儿生命体征变化及PETCO2,记录插管成功即刻及拔管时患儿MAP、HR、SPO2,观察术毕拔管时间、完全清醒时间及拔管后有无呛咳、喉头水肿、喉痉挛等并发症。结果与Ⅰ组相比,Ⅱ组插管后,HR、Bp明显低于Ⅰ组。术毕拔管时间及完全清醒时间Ⅰ组显著延长,Ⅰ组术毕拔管后并发症明显高于Ⅱ组。结论舒芬太尼用于唇腭裂修复术安全可靠,较传统麻醉方法具有术中麻醉平稳、清醒迅速、术毕并发症少等优点。Objective To investigate the feasibility of Sufentanil anesthesia to use in the babies and infants＇ primary cleft of lip or palate repair.Methods Sixty patients undergoing primary cleft of lip or palate repair were randomly divided into two groups：fentanil group（group I）,Sufentanil group（group II）,each group with thirty patients.The anesthesia induction method of group I：with intravenous injection of fentanil（4μg/kg）,propofol（2mg/kg）,vecuronium（0.1mg/kg）;group II：with intravenous injection of Sufentanil（0.5μg/kg）,propofol（2mg/kg）,vecuronium（0.1mg/kg）.After intubing.controlling patients＇breath（setting for fresh oxygen flow 2L/min） and adding vecuronium,propofol and fentanyl（group I） or Sufentanil（group II） to maintain anesthesia during operation.Meanwhile monitoring patients＇ life functional indicators change and PETCO2.Observing HR MAP and SPO2 of patients while intubing and extubing.Recording the using time of extubing postoperatively and sobering.Observing the postoperative complications of choking,periglottic edema and laryngospasm appearing whether or not after extubed.Result The value of HR and BP of the group II is obviously lower than which of the group I.After intubed the using time of sobering and extubing postoperatively of the group I is apparently more comparing with the group II and the postoperative complications taking place more times in the group I than the group II.Conclusion Sufentanil anesthesia is effective and safe with the advantages of anesthesia stability,sober rapidly and few postoperative complications comparing with traditional anesthesia method.

关 键 词：舒芬太尼 唇腭裂修复术 婴幼儿 

分 类 号：R614.24[医药卫生—麻醉学]