鼻咽癌调强放射治疗与常规放疗的剂量学比较  

Comparison of intensity modulated radiation therapy and conventional radiation therapy

作　　者：张福正[1] 邹勤舟[1] 黄剑峰[1] 车俊[1] 范强1 楚建军[1] 赵的非[1] 贺蓓娃[1] 

机构地区：[1]江苏省无锡市第四人民医院肿瘤放疗科,214062

出　　处：《中国医药》2010年第12期1182-1183,共2页China Medicine

摘　　要：目的 比较鼻咽癌调强放疗和常规放疗时肿瘤和正常组织受照剂量的差异.方法 用CMS逆向治疗计划系统分别对30例T3N1M0鼻咽癌患者进行调强放疗和常规放疗计划设计,计算肿瘤和正常组织受照射剂量.结果 调强放疗与常规放疗肿瘤所接受的剂量无明显差别（P＞0.05）,射野内垂体和左右侧腮腺、颞叶、颞颌关节受照剂量低于常规放疗[（48.6±2.5）Gy比（62.5±4.8）Gy;（41.3±2.7）Gy比（67.7±2.6）Gy,（41.5±4.2）Gy比（66.0±2.7）Gy;（25.4±6.2）Gy比（56.3±1.4）Gy,（25.4±6.6）Gy比（56.1±1.5）Gy;（41.1±4.2）Gy比（62.5±5.9）Gy,（41.9±4.8）Gy比（60.1±10.0）Gy;P＜0.05].结论 鼻咽癌调强放疗与常规放疗相比,肿瘤靶区剂量精确可靠,正常组织受照剂量得到有效控制.Objective To study and compare the dose difference of intensity modulated radiation therapy （IMRT） and conventional radiation therapy（CRT） affecting tumor and normal tissues. Methods Thirty nasopharyngeal carcinoma patients in stage T3N1M0 received IMRT and CRT with CMS system. The dose affecting tumor and normal tissues was calculated respectively. Results There was no significant difference of the dose between IMRT and CRT, but the dose affecting the normal tissue was lower in IMRT than that in CRT. Conclusions The dose distribution to tumor target area is more precise with IMRT than that with CRT. The dose to the normal tissues is controlled more effectively with IMRT than that with CRT.

关 键 词：鼻咽肿瘤 常规放疗 调强放疗 放射治疗剂量 

分 类 号：R766.3[医药卫生—耳鼻咽喉科]