Ⅱ型ZTC1+1天然澄清剂在虎杖多糖纯化中的作用  

Effect ofⅡZTC1+1 natural clarifying agents on purification of Polygonum cuspidatum polysaccharides

作　　者：孟祥海[1] 朱骤海[1,2] 张琳[1] 郭晨[1] 郑可农 李宏[1] 赵鹏[2] 

机构地区：[1]陕西新药技术开发中心,西安710075 [2]西北大学化工学院,西安710069

出　　处：《中华中医药杂志》2010年第12期2140-2142,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：陕西省科学技术研究发展计划项目[No.2007K-06(8)]~~

摘　　要：目的:考察Ⅱ型ZTC1+1天然澄清剂在虎杖多糖提取中的纯化效果。方法:以脱蛋白率、多糖保留率为指标,通过正交试验进行方法优化。结果:Ⅱ型ZTC1+1天然澄清剂能有效纯化多糖,并与澄清剂的加入量显著相关。结论:Ⅱ型ZTC1+1天然澄清剂处理虎杖多糖的理想条件为B/A组分添加量为2%/1%,药液浓度为1:15,加样温度为60℃,加热时间为1h/1h。Objective： To study the effect of Ⅱ ZTC1＋1 natural clarifying agents on the purification of Polygonum cuspidatum polysaccharides. Methodes： With the clearance rate of protein and the Polysaccharide retention as indexes, the technology was optimized by orthogonal experiment. Results： Ⅱ ZTC1＋1 natural clarifying agents can effectively purify Polygonum cuspidatum polysaccharides, which was relative to the quantity of two components. Conclusion： The optimum experimental condition is A3B2C2D1.

关 键 词：天然澄清剂 虎杖多糖 提纯 

分 类 号：R284[医药卫生—中药学]