严重急性呼吸综合症特异性记忆T细胞的研究进展  

New advances in SARS specific memory T cells

作　　者：赵恺[1] 吴长有[1] 

机构地区：[1]中山大学中山医学院免疫学教研室,广州510080

出　　处：《国际免疫学杂志》2010年第6期427-430,共4页International Journal of Immunology

基　　金：国家科技部“863”项目（2007AA022415）

摘　　要：严重急性呼吸综合症（SARS）冠状病毒可以同时诱导出体液免疫应答和细胞免疫应答。对SARS康复者血清中特异性抗体水平检测表明，其随时间推移明显降低。特异性细胞免疫应答在机体清除病毒的过程中发挥着重要的作用，尤其是特异性记忆T细胞在抵御病毒再次入侵时，能迅速产生免疫应答有效保护机体。Both of humoral and cellular immune responses can be induced by SARS coronavirus. It has been reported that the level of specific antibody is reduced in a time-dependent manner in SARS recovered patients. Cellular immune response plays an important role in antiviral immunity. Immune responses can be quickly produced by antigen-specific memory T cells to protect bodies against viruses. In this review, we summarize the recent progress of the production, maintenance and function of SARS antigen specific memory T cells.

关 键 词：严重急性呼吸综合症 记忆T细胞 疫苗 

分 类 号：R473.51[医药卫生—护理学]