抽动障碍的易感基因定位研究进展  

Progress in research on susceptibility gene mapping of Tic disorder

作　　者：李念[1] 朱翠珍[1] 黄颐[1] 

机构地区：[1]四川大学华西医院心理卫生中心,成都610041

出　　处：《中华医学遗传学杂志》2010年第5期517-520,共4页Chinese Journal of Medical Genetics

基　　金：国家自然科学基金（30870890）

摘　　要：抽动障碍是发病于儿童时期的一种慢性神经精神疾病.研究表明遗传因素在抽动障碍的发病中具有重要作用,并且该病是受多基因影响的复杂疾病.近年来抽动障碍的易感基因定位取得了一定的进展,选择鉴定了许多候选基因并对这些基因与抽动障碍的关系进行了探讨.这些研究为抽动障碍发病机制理解和以后的研究工作提供了参考.作者对近年来抽动障碍易感基因定位的研究进展作了综述.Tic disorder （TD） is a chronic neuropsychiatric disorder with childhood onset. Previous research has demonstrated that genetic factors play an important role in the pathogenesis of TD, and TD is a complex disease affected by multiple genes. Many susceptibility genes have been identified and the relationship between these genes and the etiology of TD was investigated in the past few years. These researches have yielded large valuable information as well as provided a reference for understanding the pathogenesis and further research of this disease. In this paper we reviewed the recent progress in the study on the susceptibility gene mapping of TD

关 键 词：抽动障碍 抽动秽语综合征 易感基因 关联 

分 类 号：R686[医药卫生—骨科学]