医用双相磷酸钙陶瓷的制备工艺研究  

The Study on the Preparation Technology of Medicinal Material——Biphasic Calcium Phosphate(BCP)

作　　者：张达志[1] 冷士良[1] 王存英[1] 乔卉莹[1] 

机构地区：[1]徐州工业职业技术学院化学工程系,徐州221140

出　　处：《山东陶瓷》2010年第5期8-11,共4页Shandong Ceramics

基　　金：徐州工业职业技术学院院级课题专项基金(XGY200805)

摘　　要：医用双相磷酸钙(BCP)陶瓷是β-磷酸三钙(β-TCP)和羟基磷灰石(HA)的复合体,其成分与骨矿物组成类似,在生理环境下能发生不同程度的降解,被组织吸收。通过化学沉淀法制备纳米羟基磷灰石,然后通过可溶性钙盐和磷酸盐反应工艺制得的β-磷酸三钙,最后将二者进行机械复合而制得双相磷酸钙,将所得样品用X射线衍射仪(XRD)对样品进行了表征。结果显示:所得的双相磷酸钙中掺杂有β-焦磷酸钙,但是它的结晶较好,并且可以改善双相磷酸钙陶瓷的力学性能。Medicinal material-biphasic calcium phosphate （BCP） is a kind of biomedical materials that will developed extremely vastly in the world on the nowadays, which has very good biocompatibility, biodegradation, corrosion resistance, and so on. It can be mainly used to repair human hard tissues （bones and teeth）. And the BPC is made of stable phase hydroxyapatite （HA） and unstable phase β-tricalcium phosphate （β-TCP）. In this study, there are three steps on the preparation of medicinal material -- biphasic calcium phosphate （BCP）. Firstly, the nanosized β-tricalcium phosphate powders were synthesized by the wet process. Secondly, nanohydroxyapatite particles were synthesized by chemical coprecipitation method. Finally, two kinds of powders were mixed and then were sintered in a muffle furnace. The samples were charactered by XRD. The result shows that there are a small amount of β-TCP in the HA. The BCP consists of HA, β-CCP and β-TPP. The β-CPP can improve mechanical properties of BCP.

关 键 词：双相磷酸钙 Β-磷酸三钙 羟基磷灰石 

分 类 号：TQ174.759[化学工程—陶瓷工业]