First total synthesis of marine alkaloid hyrtiosulawesine  

作　　者：Pu Yong Zhang Sheng Biao Wan Su Mei Ren Tao Jiang 

机构地区：[1]School of Medicine and Pharmacy,Key Laboratory of Marine Drugs,Ministry of Education,Ocean University of China,Qingdao 266003,China

出　　处：《Chinese Chemical Letters》2010年第11期1307-1309,共3页中国化学快报(英文版)

基　　金：financial support of Key International S&T Cooperation Projects of MOST(No. 2008DFA31040)

摘　　要：Hyrtiosulawesine was isolated from Indonesian specimens of the marine sponges Hyrtios erectus and H.reticulatu in 2002.We report here the first total synthesis of hyrtiosulawesine using an efficient and convenient synthetic strategy which could be widely used in the synthesis of otherβ-carboline compounds.All structures of new compounds were confirmed by 1H NMR,13C NMR and HRMS.Hyrtiosulawesine was isolated from Indonesian specimens of the marine sponges Hyrtios erectus and H.reticulatu in 2002.We report here the first total synthesis of hyrtiosulawesine using an efficient and convenient synthetic strategy which could be widely used in the synthesis of otherβ-carboline compounds.All structures of new compounds were confirmed by 1H NMR,13C NMR and HRMS.

关 键 词：β-Carboline Hyrtiosulawesine Pictet-Spengler reaction TRYPTAMINE Total synthesis 

分 类 号：O629.3[理学—有机化学]