Potentiometric detection of polyions based on functionalized magnetic nanopaiticles  

作　　者：De An Song Rong Ning Liang Rui Ming Zhang Jia Wang Ding Jun Zhang Wei Qin 

机构地区：[1]Key Laboratory of Coastal Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China [2]Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China [3]Graduate University of Chinese Academy of Sciences, Beijing 100049, China

出　　处：《Chinese Chemical Letters》2010年第11期1378-1381,共4页中国化学快报（英文版）

基　　金：financially supported by the Chinese Academy of Sciences(No.KZCX2-YW-410);the National Natural Science Foundation of China(Nos.40776058 and 20977073);the National 863 High Technology Project of the Ministry of Science and Technology of China(No.2007AA09Z103);the Outstanding Youth Natural Science Foundation of Shandong Province(No.JQ200814);the Taishan Scholar Program of Shandong Province

摘　　要：A novel potentiometric detection strategy based on functionalized magnetic nanoparticles has been developed for rapid and sensitive sensing of polyions.Highly dispersed magnetic nanoparticles coated with ion exchanger and plasticizer could promote an in situ cooperative ion-pairing interaction between the ion exchanger and the polyion analyte in sample solution by dramatically reducing the mass-transfer distance.With applying a magnetic field,the nanoparticles can be attached to the surface of ion exchanger free polymeric membrane.The observed potential signals are related to the polyion concentrations.The proposed polymeric membrane electrode exhibits a linear relationship between the greatest potential response slope（dE/dt） and the logarithm of protamine concentration in the range of 0.05-5μg/mL with a lower detection limit of 0.033μg/mL.A novel potentiometric detection strategy based on functionalized magnetic nanoparticles has been developed for rapid and sensitive sensing of polyions.Highly dispersed magnetic nanoparticles coated with ion exchanger and plasticizer could promote an in situ cooperative ion-pairing interaction between the ion exchanger and the polyion analyte in sample solution by dramatically reducing the mass-transfer distance.With applying a magnetic field,the nanoparticles can be attached to the surface of ion exchanger free polymeric membrane.The observed potential signals are related to the polyion concentrations.The proposed polymeric membrane electrode exhibits a linear relationship between the greatest potential response slope（dE/dt） and the logarithm of protamine concentration in the range of 0.05-5μg/mL with a lower detection limit of 0.033μg/mL.

关 键 词：POTENTIOMETRY Functionalized magnetic nanoparticles POLYIONS Ion-selective electrodes 

分 类 号：O647.316.2[理学—物理化学] Q523[理学—化学]