医院感染常见病原菌耐药性分析  

Analysis of Drug Resistance of Common Nosocomial Infection Pathogens

作　　者：刘伟[1] 冷应蓉[1] 罗光英[1] 查筑红[1] 王敏[1] 程永素[1] 杨焕婕[1] 

机构地区：[1]贵州贵阳医学院附属医院,550004

出　　处：《中国实用医药》2010年第33期64-66,共3页China Practical Medicine

摘　　要：目的了解医院常见病原菌分布及耐药状况。方法 2009年1～5月期间,我院临床感染性标本中病原菌的分布及耐药率进行回顾性分析。结果所分离的病原菌对抗菌药物均产生了较严重的耐药性,耐药率高的抗菌药物有:头孢曲松钠(94.1%),环丙沙星(91.8%),苯唑青霉素(87.0%),头孢他啶、头孢吡肟、氨曲南、复方新诺明、红霉素、(均>50.0%)。敏感率较高的抗菌药物为:万古霉素(I1.9%)、利奈唑胺(3.0%)、亚胺培南(4.0%)。结论为防止医院感染,减少ESBLs菌株的产生,控制耐药菌株的播散和流行,临床需严格控制第三代头孢菌素及其他广谱β-内酰胺类抗菌药物的使用,做到合理应用抗菌药物。Objective To know the etiology and drug resistance of common nosocomial infection pathogens.Methods The hospital carried out retrospective analysis on etiology and drug resistance of pathogens in clinical infectious sample from January to May 2009.Results Pathogens separated have all produced serious drug resistance to antibacterial agents.Agents with relatively higher drug resistance rate include：ceftriaxone sodium（94.1% ）,ciprofloxacin（91.8% ）,oxacillin（87.0% ）,ceftazidime,cefepime,aztreonam,SMZ-TMP and erythrocin（all〉 50% ） .Agents with relatively higher susceptibility rate inculde：vancomycin（11.9% ）,linezolid（3.0% ） and imipenem（4.0% ） .Conclusion In order to prevent nosocomial infection,reduce ESBLs bacterial strain and take effective measures to contorl the prevalence of bacterial strain with drug-resistance,third-generation cephalosporins and other extended-spectrum β-lactamases（ESBLs） shall be used in clinical application in strict control realize more rationally use of antimicrobial drugs.

关 键 词：病原菌 耐药性 分析 

分 类 号：R446.5[医药卫生—诊断学]