大块骨质溶解症的影像学表现(附2例报告及文献复习)  

Imaging Diagnosis of Massive Osteolysis(Report of 2 Cases and Literature Review)

作　　者：李小虎[1] 王万勤[1] 陈华平[2] 钱银锋[1] 赵韧[3] 余永强[1] 刘斌[1] 徐丽艳[1] 余长亮[1] 

机构地区：[1]安徽医科大学第一附属医院放射科,合肥230022 [2]广东省韶关市粤北人民医院影像科,512026 [3]安徽医科大学第一附属医院心血管内科,合肥230022

出　　处：《临床放射学杂志》2010年第11期1567-1569,共3页Journal of Clinical Radiology

摘　　要：目的 提高对大块骨质溶解症的影像学表现的认识。资料与方法本文报道2例影像学及病理组织明确诊断大块骨质溶解症患者,其中1例患者随访1年。结果 结合文献探讨大块骨质溶解症影像学表现:X线片可见管状骨病变残端呈"笔尖"状,扁骨病变均表现为"骨缺损"或"骨消失"。CT可见扁骨缺损边缘呈"尖角"状。MRI示正常骨髓信号消失,T1WI病灶呈与肌肉信号相近的低信号;T2WI呈明显高信号。结论 大块骨质溶解症又称Gorham-Stout综合征,是一种罕见的以大块骨质溶解为特征的骨损害。诊断主要依据影像学和病理组织学检查。组织切片检查可见骨质内脉管肿瘤样改变。Objective To improve imaging diagnosis knowledge of Massive Osteolysis.Materials and Meth-ods This paper reports two cases of radiological and pathological diagnosis in patients with massive osteolysis,including one cases of clinical follow-up for 1 year.Results Combination of literature review large osteolysis imaging X-ray shows bone lesions stump was ＂pen＂-shaped,flat bone lesions appeared as ＂bone defects＂ or ＂bone loss＂ CT shows bone defect edges bian ＂cusp＂ shape.MRI showed normal bone marrow signal disappeared,T1WI lesion and muscle signal was similar to the low signal;T2WI showed significantly higher signal.Conclusion Gorham-Stout syndrome is a very rare disease characterized by massive osteolysis.The diagnosis must be confirmed by radiological and histological findings.Biopsy reviews always reveal intramedullary angioma-like vascular structures.

关 键 词：骨质溶解 原发性 诊断显像 

分 类 号：R816.8[医药卫生—放射医学]