质子泵抑制剂预防非甾体类抗炎药相关性胃病的研究进展  

Advances in prevention of nonsteroidal anti-inflammatory drug-induced gastropathy by proton pump inhibitor

作　　者：郑力搏[1] 张晓岚[1] 

机构地区：[1]河北医科大学第二医院消化科,河北省消化病重点实验室,河北省消化病研究所,河北石家庄050000

出　　处：《中国病理生理杂志》2010年第11期2274-2278,2283,共6页Chinese Journal of Pathophysiology

摘　　要：Nonsteroidal anti-inflammatory drugs (NSAIDs) are powerful in anti-inflammatory, analgesic and antirheumatic effects,and widely used in treating the corresponding diseases. Over the years, many new dosage forms and structures of NSAIDs appear since aspirin was developed 112 years ago. However, the universal use of NSAIDs produces unavoidable mucosal lesions in gastrointestinal tract. As yet, proton pump inhibitor (PPI) has been used in the treatment of gastropathy induced by NSAIDs. This article will focus on the advances in prevention of NSAIDs-induced gastropathy by proton pump inhibitor.Nonsteroidal anti-inflammatory drugs （NSAIDs） are powerful in anti-inflammatory, analgesic and antirheumatic effects, and widely used in treating the corresponding diseases. Over the years, many new dosage forms and structures of NSAIDs appear since aspirin was developed 112 years ago. However, the universal use of NSAIDs produces unavoidable mucosal lesions in gastrointestinal tract. As yet, proton pump inhibitor （PPI） has been used in the treatment of gastropathy induced by NSAIDs. This article will focus on the advances in prevention of NSAIDs-induced gastropathy by proton pump inhibitor.

关 键 词：质子泵抑制剂 非甾体类抗炎药相关性胃病 

分 类 号：R452[医药卫生—治疗学]