双肾嗜酸细胞瘤2例报告及文献复习  

Bilateral renal oncocytomas:Report of 2 cases and review of literature

作　　者：钱友良[1] 费翔[1] 张墨[1] 罗金玉[1] 李书剑[1] 宋永胜[1] 

机构地区：[1]中国医科大学附属盛京医院泌尿外科,辽宁沈阳110004

出　　处：《现代肿瘤医学》2010年第12期2419-2421,共3页Journal of Modern Oncology

摘　　要：目的:提高双侧肾脏嗜酸细胞瘤的诊治水平。方法:回顾分析2例双肾嗜酸细胞瘤患者的临床资料,结合文献复习并讨论。结果:例1术前疑诊为双肾嗜酸细胞瘤,一侧术中快速冰冻病理证实,行保留肾脏的肿瘤剜除术,另一侧穿刺证实。另一例术前诊断双侧肾癌,行根治性左肾切除,及右肾穿刺活检术,病理均诊断肾嗜酸细胞瘤,术后分别随访3年及10个月,未见肿瘤复发,转移。结论:肾嗜酸细胞瘤系肾脏良性肿瘤,多为单发,极少数双侧发病,术前诊断较困难,应依据免疫学、影像学、病理组织学等综合诊断。治疗以保肾手术为首选。双肾及多发肾嗜酸细胞瘤,术前穿刺活检或术中冰冻病理检查极其重要,并应尽量选择保肾手术,但术后应密切随访。Objective：To improve the diagnosis and treatment of bilateral renal oncocytomas.Methods：The clinical data of 2 cases with bilateral renal oncocytomas were retrospectively analyzedand and with literature review.Resuits：One Case diagnosed suspiciously as bilateral renal oncocytomas before operation and proved by pathology in operation underwent tumor excision with the kidney reserved,the other side was diagnosed by biopsy.The other patient was misdiagnosed to bilateral renal cell carcinomas before operation,undrwent a left nephrectomy and a biopsy of the right kidney,two sides were diagnosed as oncocytoma by histological.Two patients were followed-up for 3 years and 10 months without metastasis or recurrence.Conclusion：Renal oncocytoma is a type of benign,parenchymatous tumor,and has no specific clinical feature.The diagnosis can be established on histopathologic,immunohistochemical and electron microscopic studies.Kidney-preserving surgical operation is the first choice treatment.It is very importent to perform biopsy before operation or frost pathologic examine during operation for bilateral and/or multifocal lesions.Kidney-preserving surgical operation,shoulded be choose as far as possible but follow up is essential.

关 键 词：双肾嗜酸细胞瘤 诊断 治疗 

分 类 号：R737.11[医药卫生—肿瘤]