痰涤雾化液治疗重型颅脑损伤气管切开术后肺炎的疗效观察  

Therapeutic effect of Tandi atomization on nosocomial acquired pneumonia afer tracheotomy in patients with severe craniocerebral injury

作　　者：苏建斌[1] 周兆祥[2] 吴铁军[1] 武华杰[1] 张伟[1] 暨朝林[1] 

机构地区：[1]湖南中医药大学第二中西医结合医院 [2]浏阳市中医医院,湖南浏阳410300

出　　处：《湖南中医药大学学报》2010年第9期171-174,共4页Journal of Hunan University of Chinese Medicine

基　　金：湖南省自然科学基金资助项目(07JJ6712)

摘　　要：目的观察痰涤雾化液治疗重型颅脑损伤经皮气管切开术后医院获得性肺炎的疗效。方法将67例重型颅脑损伤经皮气管切开术后并发医院获得性肺炎的患者随机分为治疗组35例,对照组32例。2组均予西医综合治疗,在此基础上,治疗组采用微量注射泵持续气道给药湿化加自拟痰涤雾化液高频氧气雾化吸入;对照组采用微量注射泵持续气道给药湿化加氨溴索注射剂高频氧气雾化吸入,比较两组疗效。结果经7 d治疗后,治疗组的白细胞数、C反应蛋白以及中医证候积分下降比对照组明显,两组间比较差异有统计学意义(P<0.05);治疗组中医证候疗效的总有效率为77.1%高于对照组的总有效率62.5%,两组间比较差异有统计学意义(P<0.05)。结论痰涤雾化液高频氧气雾化吸入治疗重型颅脑损伤气管切开术后并发医院获得性肺炎的患者疗效确切,安全无明显副作用,值得临床推广。Objective To evaluate the efficacy of Tandi atomization on nosocomial acquired pneumonia in patients with sever craniocerebral injury afer tracheotomy.Methods 67 patients were divided into two groups,35 patients in treatment group and 32 in control group.On the basis of systematic treatment with western medicine,Tandi atomization inspiration was given to in treatment group and ambroxol in control group.Results After treatment 7 days,the white blood cell count,C-reactive protein（CRP）,and symptom scores in treatment group decreased significantly than tnat in control group（P0.05）;the total effective rate in treatment group was 77.1% and in control group 62.5%（P0.05）.Conclusion Tandi atomization is definitely effective,safe and less side-effect for the disease,and may beused in clinic.

关 键 词：重型颅脑损伤 气管切开术后 医院获得性肺炎 雾化吸入 痰涤雾化液 

分 类 号：R651.1[医药卫生—外科学]