2型糖尿病合并非酒精性脂肪肝患者的相关因素分析  

Analysis of related factors of type 2 diabetes complicated with nonalcoholic fatty liver

作　　者：刘鹏举[1] 马方[1] 楼慧萍[1] 杜春炜[1] 陶鑫[1] 

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院营养科,北京100730

出　　处：《中国现代医学杂志》2010年第2期270-273,共4页China Journal of Modern Medicine

摘　　要：目的探讨2型糖尿病合并非酒精性脂肪肝患者和未合并脂肪肝患者人体测量指标和血脂的差异以及体重指数、腰围与脂肪肝的相关性。方法回顾性分析57例2型糖尿病合并脂肪肝患者及同时期81例未合并脂肪肝的2型糖尿病患者的临床资料。结果2型糖尿病合并脂肪肝患者的体重指数(BMI)、腰围(WC)、臀围(HC)、腰围/臀围(WHR)和甘油三酯水平(TG)显著高于未合并脂肪肝患者(P<0.05),而总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-c)和低密度脂蛋白胆固醇(LDL-c)的水平两组间无显著差异(P>0.05);脂肪肝组血脂异常的发生率大于未合并脂肪肝组(P<0.05)。结论2性糖尿病患者合并脂肪肝与血脂代谢紊乱、肥胖相关;2型糖尿病患者中脂肪肝的发生率随BMI和腰围的增大而增高。【Objective】To explore the difference of anthropometric parameters and serum lipid profiles between type 2 diabetes patients with and without nonalcoholic fatty liver,and the correlation between fatty liver and body mass index（BMI）,waist circumstance（WC）.【Methods】The clinical data of 57 cases of type 2 diabetes patients with nonalcoholic fatty liver and concurrent 81 cases of type 2 diabetes patients without nonalcoholic fatty liver were analyzed retrospectively.【Results】The WC hip circumstances（HC） were longer,BMI,waist-hip ratios（WHR） and serum triglycerides（TG） were higher in patients with nonalcoholic fatty liver than those in patients without nonalcoholic fatty liver（P0.05）,while there were no significant differences in total cholesterols（TC）,high density lipoprotein-cholesterols（HDL-c） and low density lipoprotein-cholesterols（LDL-c） between the two groups（P 0.05）.The incidence of dyslipidemia in nonalcoholic fatty liver group is higher than that in the group without nonalcoholic fatty liver（P0.05）.【Conclusion】Patients with type 2 diabetes complicated with nonalcoholic fatty liver are associated with dyslipidemia and obesity,and the incidence of nonalcoholic fatty liver in patients with type 2 diabetes rises as the BMI and WC increase.

关 键 词：2型糖尿病 非酒精性脂肪肝 人体测量 体重指数 腰围 血脂异常 

分 类 号：R587.1[医药卫生—内分泌]