正常人服氯氮平后脑电图的动态变化  

EEG changes in normal subjects after clozapine

作　　者：吕路线[1,2] 郭素芹[1,2] 尚景瑞 郭云[1,2] 李全会 白长喜[1,2] 石玉中 李淑英[1,2] 

机构地区：[1]河南省精神病医院 [2]河南新乡市职业病防治研究所

出　　处：《临床精神医学杂志》1999年第2期79-80,共2页Journal of Clinical Psychiatry

摘　　要：目的：探讨氯氮平对正常人脑电活动的影响。方法：应用定量药物脑电图对７例正常人进行了自身前后对照研究。结果：口服一次量２５ｍｇ氯氮平后，在２～４小时出现明显脑电变化，主要变化为δ及θ频段能量增加，α２频段能量减少。结论：定量药物脑电图能反映人脑的功能变化。Objective:To study changes of electrical activity of brain after taking clozapine in normal subjects. Method:Seven normal subjects were examined with quantitative pharmaco EEG before and after taking clozapine. Results:Significant change in EEG occurred after taking 25mg clozapine for 2 to 4 hours.There was increased δ and θ waves with decreased α 2 activities. Conclusion:Quantitative pharmaco EEG could be used to reflect dynamic changes of brain function.

关 键 词：定量药物 脑电图 氯氮平 

分 类 号：R971.3[医药卫生—药品]