丝素在肌腱缺损修复中的应用  

Application of Silk Fibroin in Repair of Tendon Defects

作　　者：黄国平[1] 陈克平[1] 

机构地区：[1]江苏大学生命科学研究院食品与生物工程学院,江苏镇江212013

出　　处：《安徽农业科学》2010年第33期18863-18865,共3页Journal of Anhui Agricultural Sciences

基　　金：江苏省科技支撑计划(社会发展)项目(BE20100705);中国博士后科学基金资助项目(20090451175);江苏省博士后科研资助计划项目(0901079C);江苏大学高级专业人才科研启动基金项目(08JDG035)资助

摘　　要：丝素具有与肌腱相似的力学性能、良好的生物相容性能和加工性能。以丝素为材料构建成的组织工程肌腱具有独特的综合优势。笔者简要综述了丝素用于肌腱缺损修复的性能,包括力学性能、生物相容性能和生物降解性能;丝素的制备与加工方式;丝素在肌腱缺损修复中的应用及问题,并展望了丝素在肌腱缺损修复中的应用前景。Silk fibroin has mechanical properties similar to tendons,good biocompatibility and good processing performance.There are unique comprehensive advantages to construct tissue-engineering tendons using silk fibroin.We briefly reviewed the properties of silk fibroin suitable for repair of tendon defects,including mechanical properties,biocompatibility and biological degradation;silk fibroin preparation and processing;the application of silk fibroin in the repair of tendon defects and its problems.Moreover,the application prospect of silk fibroin in the repair of tendon defects is predicted.

关 键 词：丝素 肌腱缺损 组织工程肌腱 

分 类 号：R686[医药卫生—骨科学]