新生儿缺氧缺血性脑病43例临床与预后分析  

Newborn hypoxic ischemic encephalogathy: A retrospective clinical and prognostic analysis of 43 cases

作　　者：黄淑贞[1] 孔庆梅[1] 李宏[1] 周媛[1] 王励 

机构地区：[1]广西柳州铁路局中心医院

出　　处：《右江民族医学院学报》1999年第2期183-184,共2页Journal of Youjiang Medical University for Nationalities

摘　　要：分析新生儿缺氧缺血性脑病（ＨＩＥ）４３例。有宫内窘迫史者占５８１％，出生重度窒息占８１４％。ＨＩＥ轻度１０例，中度２６例，重度７例。合并心肌损害达４１７％。治愈好转率为８１３％。病死率７０％。随访２４例，轻度ＨＩＥ预后好，中度有明显后遗症者为６７％，重度预后不良。认为加强围生期保健，提高产科质量，进行新法复苏及复苏后处理是降低ＨＩＥ发病率的关键。诊治中应重视心肌损害。使用胞二磷胆碱等脑细胞代谢激活剂辅治ＨＩＥ效果肯定。对于预后，强调早期治疗，早期评分、早期随访、早期干预是改善重度ＨＩＥ预后的几个重要环节。Forty-three newborns (male 31, femal 12) with hypoxic ischemic encephalogathy (HIE) have been reptrospectively analyzed, 58 1 percent of them with history of intrauterine distress and 81 4 percent with asphyxia. Ten cases are mild, twenty-six are middle, and seven are severe. The follow up of 24 cases showed that mild HIE had good prognosis, 6 7 percent of middle symptom had a distinct sequel, and the severe patients had a poor prognosis. It is thought that the key to reduce the attack rate of HIE is to strengthen the health care in the perinatal period, to raise the obstetric quality, to use new method of resuscitation, and to treat properly after the resuscitation. It should pay great attention to cardiac muscle damage. It is ensured that the effect of citicocine is good for HIE. It is suggested that the important link of improving prognosis of severe patients with HIE is treatment, evaluation of work points, follow-up, and intervene all in earlier.

关 键 词：新生儿 缺氧缺血性脑病 预后 临床 

分 类 号：R722.120.7[医药卫生—儿科]