3-甲基-2-丁烯酸的合成研究  

Study on Synthesis of 3-methyl-2-butenoic Acid

作　　者：钱洪胜 鲁国彬 董金锋 商志才[2] 

机构地区：[1]浙江新和成股份有限公司,浙江新昌312500 [2]浙江大学理学部,浙江杭州310027

出　　处：《化工时刊》2010年第11期23-26,共4页Chemical Industry Times

基　　金：浙江省重大科技专项(优先主题)工业项目(2008C11053)

摘　　要：以廉价的2-甲基-3-丁炔-2-醇为原料,经迈耶-舒斯特重排反应得到3-甲基-2-丁烯醛,再经空气氧化制得标题化合物。对重排反应条件和氧化反应条件等工艺条件进行了详细研究。结果表明,以液体石蜡为溶剂,115～125℃催化重排反应3 h,处理后可得含量为98%的3-甲基-2-丁烯醛,收率85%以上;3-甲基-2-丁烯醛以微量氯化亚铜为催化剂,35℃以下通空气氧化,得到含量为97.5%的3-甲基-2-丁烯酸,收率90%以上。该方法原料廉价易得,工艺路线短,收率较高,对环境友好,是一种有前途的方法。The effective method of synthesis of 3-methyl-2-butenoic acid,the cheap 2-Methyl-3-butyn-2-ol was taken as starting material,by Meyer-Schuster rearrangement to 3-Methyl-2-butenal.After oxidized 3-Methyl-2-butenal by air,the title compound was obtained.The conditions of Meyer-Schuster rearrangement and oxidation reaction were investigated in detail.The result showed that using liquid paraffin as solvent,rearrangement reacting at 115～125℃ for 3 hrs,3-methyl-2-butenal 85% yield with more than 98% purity was obtained.Using traces CuCl as catalyst,blowing air into 3-methyl-2-butenal below 35℃,3-methyl-2-butenoic acid 90% yield with more than 97.5% purity was obtained.The method was considered a good one with advantages such as short procedure,high yield,starting material cheap and easy to get and environmentally friendly.

关 键 词：3-甲基-2-丁烯醛 3-甲基-2-丁烯酸 有机合成 

分 类 号：TQ225.134[化学工程—有机化工]