心脏肌钙蛋白T低水平升高的临床分布及意义初探  

Analysis of the distribution and meanings of low-level increased cardiac troponin T

作　　者：吕杨[1] 颜保松[1] 郝家明[1] 

机构地区：[1]中国人民解放军第187中心医院检验科,海南海口571159

出　　处：《海南医学》2010年第22期27-29,共3页Hainan Medical Journal

摘　　要：目的对心脏肌钙蛋白T低水平升高的分布情况进行分析。方法回顾本院自开展心脏肌钙蛋白T检测以来的所有临床结果,按照正常人群的99百分位点和急性冠脉综合征的临床阈值为数据的分区标准,对介于二者间的结果进行分析和讨论。结果心脏肌钙蛋白T处于低水平升高的检测结果占总检测例数的9.69%(1 228例中有119例),以急性冠脉综合征为最多,其次是2型糖尿病、肿瘤、高血压、烧伤和脑梗塞。其中23例最后发展为心肌梗死。结论心脏肌钙蛋白T的低浓度升高可见于多种疾病,与心肌损害密切相关,部分会发展到心肌梗死,须密切关注。Objective To analyze the distribution of increased troponin T between 0.01 ng/ml and 0.1ng/ml in patients.Methods Based on the healthy upper reference limit（99th percentile） for troponin T0.01 ng/ml and the cutoff（clinical discriminator） value 0.1 ng/ml,1228 tests of cTnT was classified to three groups.Results Of all the cases,67.67% was normal（831of 1228）,22.64% was over cutoff（278 of 1228）,and 9.69%（119 of 1228） was between the upper reference limit and clinical discriminator which includes ACS,type II diabetes mellitus,tumor,hypertension,burns and cerebral infarction.Conclusions Low-level increased troponin T less than clinical discriminator can be detected in many diseases and some of them will develop AMI,so we should pay attention to the changes of these cases.

关 键 词：肌钙蛋白T 急性心肌梗死 糖尿病 

分 类 号：R446.6[医药卫生—诊断学]