交联聚苯乙烯微球的表面化学改性及吡啶基卟啉的固载化  

Surface Chemical Modification of Crosslinked Polystyrene Microspheres and Immobilization of Pyridyl Porphyrins

作　　者：田鹏[1] 高保娇[1] 张妍妍[1] 

机构地区：[1]中北大学化学工程系,太原030051

出　　处：《应用化学》2010年第12期1376-1380,共5页Chinese Journal of Applied Chemistry

基　　金：山西省自然科学基金资助项目(2008021013)

摘　　要：以无致癌毒性的1,4-二氯甲氧基丁烷为氯甲基化试剂,先将交联聚苯乙烯(CPS)微球氯甲基化,制得氯甲基化微球CMCPS。然后使微球CMCPS与4-吡啶甲醛进行季铵化反应,将4-吡啶甲醛键合到CPS微球表面,制得键合吡啶甲醛(PyAL)的改性微球PyAL-CPS。考察了主要反应条件对季铵化反应的影响,最终确定季铵化反应的优化条件:溶剂CCl4,反应温度60℃,最后使改性微球PyAL-CPS、4-吡啶甲醛及吡咯在固-液界面上进行Adler反应,形成固载吡啶基卟啉(PyP)的微球PyP-CPS。用IR和UV-Vis以及Zn2+配合物生成法表征了微球PyP-CPS的形成及负载量。Crosslinked polystyrene microspheres（CPS） were first chloromethylated with non-carcinogenic 1,4-bis（chloromethoxy） butane（BCMB） to form chloromethylated microspheres（CMCPS）.Then quaternization reaction between CMCPS microspheres and 4-pyridylaldehyde was carried out to modify the CPS microspheres with 4-pyridylaldehyde（PyAL-CPS）.The effects of main factors on the quaternization reaction were examined,and the synthetic conditions were optimized.The suitable temperature and appropriate solvent are 60 ℃ and CCl4,respectively.Finally,Alder reaction at the interface of solid/solution between 4-pyridylaldehyde on the surface of modified microspheres and pyrrole was performed to form the functional microspheres（PyP-CPS）,on which the formation of pyridyl porphyrin（PyP） could be achieved.The PyP-CPS formation were characterized by using IR and UV-Vis while and the loading of PyP was demonstrated by forming Zn-PyP complex.

关 键 词：交联聚苯乙烯微球 吡啶甲醛 季铵化反应 吡啶基卟啉 固载 

分 类 号：O631[理学—高分子化学]