早期梅毒血清固定患者血清IL-2、IL-10检测及意义  

Clinical Significance of Serum IL-2 and IL-10 in Patients with Early Syphilis Sero-resistant

作　　者：陈星[1] 叶和军[1] 赵建平[1] 翁瑞全[2] 

机构地区：[1]武警浙江总队医院,嘉兴314000 [2]重庆医科大学附属第二医院,重庆400010

出　　处：《实用中西医结合临床》2010年第6期69-70,共2页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:探讨IL-2、IL-10与早期梅毒血清固定形成的关系。方法:采用ELISA法检测20例梅毒血清固定患者IL-2、IL-10浓度,同时以20例经治疗后血清反应阴性梅毒患者及30例健康献血者为对照。结果:与阴转组和正常组比,试验组患者IL-2水平较低,而IL-10水平较高(P<0.05);阴转组和正常组IL-2及IL-10水平差异无显著性(P>0.05)。结论:早期梅毒血清固定的形成可能与Thl/Th2比例失衡有关。Objective：To explore the relationship between the levels of IL-2,IL-10 and the sero-resistant form of early syphilis.Methods：The serum levels of IL-2,IL-10 were measured by ELISA in 20 patients with early sero-resistant syphilis patients,20 patients with negative results after treatment and 30 healthy controls.Results：The level of IL-2 was lower and the level of IL-10 was higher,compared with those of the controls（P〈0.05）.However,there was no difference in the levels of IL-2,IL-10 between the controls（P〈0.05）.Conclusion：There is a correlation between the imbalance of Thl/Th2 reaction and the sero-resistant form of early syphilis.

关 键 词：血清固定 梅毒 白细胞介素2 白细胞介素10 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]