近红外漫反射光谱在脱水剂脱水作用中的应用研究  

Application of near infrared diffusion spectrum in effect of anhydration solution

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作  者:戴丽娟[1] 花国然[1] 钱志余[2] 

机构地区:[1]南通大学机械工程学院,江苏南通226019 [2]南京航空航天大学生物医学工程系,江苏南京210016

出  处:《量子电子学报》2010年第6期737-742,共6页Chinese Journal of Quantum Electronics

基  金:国家自然科学基金(30671997);江苏省自然科学基金(BK2008184);南通市自然科学基金(K2009044)资助项目

摘  要:分析了脑局部皮层的近红外漫反射光谱在研究脱水剂脱水作用中的可行性。将60只SD大鼠随机分成A、B、C三组,每组分别在尾静脉推注0.9%NaCl、20%甘露醇和7.5%NaCl(均为10 ml/kg),利用双光纤微创探头实时在位采集推注前后大鼠局部脑皮质的近红外漫反射光谱,分析光谱变化。A组(0.9%NaCl)推注前后光谱未见明显变化,B组(20%甘露醇)和C组(7.5%NaCl)推注后近红外区光谱斜率绝对值的相对变化率分别上升(5.5±1.2)%和(10.5±2.5)%,三组间的差别存在统计学意义。可见,脑局部皮质的漫反射光谱可作为一种评估脱水剂脱水作用的新方法。The feasibility of the near infrared diffusion spectrum of local cortex for study of effect of anhydration solution is analyzed. 60 SD rats were divided in random into three groups A, B, C, which are treated by 0.9% NaCl, 20% mannitol and 7.5% NaCl through vena cava respectively. The near infrared diffusion spectrum of local cortex were collected continuously before and after the injection by a bifurcated fiber probe in vivo in a mini-invasive way. Then the changing rules of the spectrum were analyzed. Few changes of the spectrum were observed in the group A(0.9% NaCl), while, relative changes of the absolute value of the spectrum slope between near infrared range increased by (5.5 ± 1.2)% for group B (20% mannitol) and (10.5 ± 2.5)% for group C (7.5% NaCl). The differences among three groups make statistic sense (p 〈 0.05). The near infrared diffusion spectrum of local cortex can be used as a new method for estimation of effect of anhydration solution.

关 键 词:光谱学 脱水作用评估 近红外漫反射光谱 脑皮层 大鼠 

分 类 号:O434.19[机械工程—光学工程] TP274[理学—光学]

 

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