血清铁蛋白水平预测急性肺损伤发生的临床应用价值  

EVALUATION OF SERUM FERRITIN AS A PREDICTOR OF THE ACUTE LUNG INJURY

作　　者：徐德斌[1] 刘树芬[1] 张劭夫[1] 蒋永艳[1] 陈秋华[1] 

机构地区：[1]济南军区总医院呼吸内科

出　　处：《中国现代医学杂志》1999年第4期14-15,共2页China Journal of Modern Medicine

摘　　要：应用放射免疫分析法前瞻性检测１７６例发生急性肺损伤（ＡＬＩ）高危因素的患者血清铁蛋白水平，随后５６例发生了ＡＬＩ。结果发现高危患者血清铁蛋白水平显著高于正常对照组（Ｐ＜０．０１），高危患者发展为ＡＬＩ者又显著高于未发展为ＡＬＩ者（Ｐ＜０．０１），女性以＞２８０μｇ／Ｌ预测ＡＬＩ灵敏度为８０．９％，特异度８６．８％，男性以＞６３０μｇ／Ｌ预测ＡＬＩ灵敏度为８５．７％，特异度８８．１％。结果表明血清铁蛋白水平可作为预测ＡＬＩ发生的良好指标用于临床。Objective:To evaluate serum ferritin as a predictor of acute lung injury (ALI).Serum ferritin levels in 176 patients at risk for ALI were measured by radioimmunoassay.The results showed that serum ferritin levels were greater in risking patients than in healthy control subjects ( P <0.01).Serum ferritin levels were also greater in risking patients who developed ALI than those in patients who did not develop ALI.In Female,a value exceeding 280μg/L predicted ALI with sensitivity of 80.9% and specificity of 86.8%.In male,a value exceeding 630μg/L predicted ALI with a sensitivity of 85.7% and specificity of 88.1%.These results suggest that serum ferritin levels may be a predictor of ALI.

关 键 词：急性 肺损伤 血清 铁蛋白 预测 

分 类 号：R563.04[医药卫生—呼吸系统]