2000年-2009年我院细菌耐药性监测结果分析  

Drug Resistance Suveillance Results of Bacteria in 2000-2009 years

作　　者：侯晓娜[1] 刘珊[1] 郑欣[1] 林育红[2] 唐莉[1] 曹丹[1] 杨婧[3] 薛文成[3] 王璐[3] 

机构地区：[1]沈阳军区总医院感染控制科,辽宁沈阳110016 [2]沈阳军区总医院呼吸科,辽宁沈阳110016 [3]沈阳军区总医院检验科,辽宁沈阳110016

出　　处：《中国实验诊断学》2010年第11期1744-1747,共4页Chinese Journal of Laboratory Diagnosis

摘　　要：目的监测临床病原菌的耐药性变迁。方法统计2000年1月-2009年12月临床送检标本中分离的病原菌及药敏结果 ,统计分析采用WHONET5.0软件。结果 10年间共检出病原菌30890株,02年以后铜绿假单胞菌由第二位上升到第一位,肺炎克雷伯菌由第一位降到第二、四位;08年后鲍曼不动杆菌排在了第二位,且泛耐药鲍曼不动杆菌占80%以上;产超广谱-β内酰胺酶(ESBLs)革兰阴性杆菌和耐甲氧西林葡萄球菌(MRS)07年前呈逐年上升趋势,08年后有所下降。结论本院病原菌的耐药性变迁符合全球细菌耐药性总趋势,但也有其特殊性。继续抓好细菌耐药性监测,特别是多重耐药铜绿假单胞菌、ESBLs、MRS和泛耐药鲍曼不动杆菌的监测及防控工作。Objective To survey the drug resistance variation of pathogens.Methods We analysed all the pathogens isolated from January 2000 to December 2009 and the drug resistance results.WHONET5 software was used to analyse the data.Results A total of 30890 pathogens were detected in ten years.P.aeruginosa rises from second to first,K.pneumonia drops from the first to second to four since 2000;A.baumannii come in the second,and the PDR-A.baumannii account for more than 80%;extended spectrum β-lactamase-Producing gram negative bacilli and MRS increased years by year before 2007 but declines after 2008.Conclusion The resistance variation of pathogens in our hospital consists with the global tendency of bacteria resistance.But also has its characteristics.The resistance surveillance should be continued especially the monitoring and prevention for MDR-P.aeruginosa 、ESBLs 、MRS、and PDR-A.baumannii.

关 键 词：病原菌 耐药性 监测 

分 类 号：R446.5[医药卫生—诊断学]