吉林某地2005-2009年分离病原菌临床特征及分布变迁  

The clinical feature and classification of pathogenic bacteria during 2005-2009 in Jilin area

作　　者：鞠晓红[1] 宿丽娟[2] 马爱新[1] 

机构地区：[1]吉林医药学院病原教研室,吉林吉林132013 [2]吉化集团总医院检验科,吉林吉林132021

出　　处：《中国实验诊断学》2010年第11期1748-1751,共4页Chinese Journal of Laboratory Diagnosis

摘　　要：目的了解吉林某地5年来临床分离病原菌的分布特征及分类变化,为临床抗感染治疗提供科学依据。方法收集2005年1月至2009年12月各类临床标本,采用法国生物梅里埃公司API试条进行细菌鉴定,并分析其变迁趋势。结果共分离细菌1 239株,其中革兰阴性杆菌居优势地位。各年度细菌总体分布情况相差不大,检出率依次为肠杆菌科细菌、革兰阳性球菌和非发酵革兰阴性菌,但单个菌种存在差别,大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌、沙雷菌、表皮葡萄球菌存在变迁趋势。结论细菌的菌群分类呈变迁趋势,临床应根据本单位、本地区的病原菌检出情况合理选择抗感染治疗方案,提高感染性疾病的早期治疗质量。Objective To investigate the distributions and classification of pathogenic bacteria clinically isolated in Jilin area for five consecutive years in order to provide rational anti-infective therapy in clinic.Methods To collect all clinical samples from January 2005 to December 2009.All of the isolated bacteria were identified with API identified test,with which the distribution characteristic and vicissitude was analyzed.Results A total of 1239 strains of bacteria were isolated.Gram negative bacilli are the major pathogens.Population distribution of pathogenic bacteria was similar.The height of isolation rate of bacteria was as follows in order：Enterobacteriaceae,Gram positive coccus and nonfermenters Gram negative bacilli.Howerver,there were vicissitude of some strains inclusion Escherichia coli,Klebsiella pneumoniae,Enterobacter cloacae,Serratieae,Staphylococcus epidermidis between 2005 to 2009.Conclusion There are obviously vicissitudes of bacteria classification in different years.Clinician should select reasonably anti-infective treatment plan according to pathogenic bacteria in local hospital and to increase early treatment effect.

关 键 词：病原菌 感染 分布变迁 

分 类 号：R446.5[医药卫生—诊断学]