芪附汤及其组方对阳虚小鼠免疫功能的影响  

Effect of Qifu Decoction and Its Components on Immunological Function of Mice with Deficiency of Vital Function

作　　者：董群[1,2] 鲁义东[1,2] 吴敏毓[1,2] 

机构地区：[1]皖南医学院微生物学教研室 [2]安徽医科大学临床药学研究室

出　　处：《中国实验方剂学杂志》1999年第3期15-17,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金

摘　　要：探讨芪附汤及其组方对阳虚小鼠免疫功能的影响。结果，芪附汤可明显增强阳虚小鼠腹腔巨噬细胞（Ｍ）的活性，红细胞Ｃ３ｂ受体（ＲＢＣ－Ｃ３ｂＲ）花环形成率、脾细胞产生抗体的能力及白介素２（ＩＬ－２）的活性，增强红细胞免疫复合物（ＲＢＣ－ＩＣ）花环形成率和脾细胞增殖反应。黄芪水煎液能促进阳虚小鼠的腹腔Ｍ的活性和ＩＬ－２的活性，增强脾细胞产生抗体的能力，但作用不及芪附汤。附子水煎液能促进阳虚小鼠脾细胞产生抗体。The purpose of the experiment is to investigate the effects of Qifu decoction and its components on the immunological function of the mice with deficiency of vital function(DVF).The results showed that Qifu decoction could evidently improve the activity of the peritoneal macrophage,increase rossette forming percentage of RBC C 3b R,facilitate the antibody formation of spleen cell and the activity of IL 2,promote the rossette forming percentage of RBC IC and proliferative reaction of spleen cell.Milk vetch root could promote the activity of peritoneal Mφ and IL 2,improve the antibody formation of spleen cell of the mice with deficiency of vital function,but is less effective than Qifu decoction.Mank shood root could improve the antibody formation of spleen cell of the mice with DVF,and the effect is similar to Qifu decoction.

关 键 词：芪附汤 附虚 免疫功能 组方 

分 类 号：R285.5[医药卫生—中药学] R241.3[医药卫生—中医学]