奶牛亚临床酮病血液生化指标消长规律的研究  

Study on Changes of Blood Biochemical Metabolites for Subclinical Ketosis in Dairy Cows

作　　者：贾宗菲[1] 石建朋[1] 韩一超[2] 庞全海[1] 

机构地区：[1]山西农业大学兽医科学研究所,太谷030801 [2]山西省农业科学院畜牧兽医研究所,太原030032

出　　处：《畜牧兽医学报》2010年第11期1490-1496,共7页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家科技支撑计划子课题(2007BAD56B06-2);山西省科技攻关项目(021044)

摘　　要：本文以血清β-羟丁酸(BHBA)含量大于1.2mmol·L-1的12头奶牛为试验组,另挑选年龄、胎次、体况与试验组奶牛相近的血清BHBA含量小于或等于1.2mmol·L-1的12头奶牛为对照组。分别于产前14、7、1d,产后第1、7、14、21、28天测定2组奶牛各血液生化指标的含量,并分析各组指标在试验期间的动态变化趋势。结果表明:试验组奶牛血清BHBA含量极显著高于对照组(P<0.01),非酯化脂肪酸(NEFA)水平显著高于对照组(P<0.05),葡萄糖(GLU)浓度极显著低于对照组(P<0.01);尿素氮(BUN)含量极显著高于对照组(P<0.01);其它指标在不同时间差异均不同。试验组和对照组奶牛血清BHBA含量在产后第7-21天处于高水平,NEFA含量在产后第21天达最高,丙氨酸氨基转移酶(ALT)和门冬氨酸氨基转移酶(AST)活性在产后第7天最高。试验证明,奶牛亚临床酮病在产后7d即可发生,在产后21d左右处于易发期。In this study,24 cows with similar age,birth and body condition were chosen and grouped by serum β-hydroxybutyric acid（BHBA） content.The cows with greater BHBA content（1.2 mmol·L-1） were assigned as the experiment group,and cows with less BHBA content（≤1.2 mmol·L-1） were assigned as the control group.The concentration of biochemical indicators in the serum which taken at the 14th,7th,1st day of prenatal and the 1st,7th,14th,21th,28th day of postpartum,were tested and the changing trends of them during the experimental stage were analyzed.The results shown that the concentration of serum BHBA in the experiment group was very significantly higher than that in the control group（P0.01）;nonesterified fatty acid（NEFA） was significantly higher than that in the control group（P0.05）;glucose（GLU） was very significantly lower than that in the control group（P0.01）;blood urea nitrogen（BUN） was very significantly higher than that in the control group（P0.01）;Other indices were difference in different stages.In the two groups,the concentration of serum BHBA was in a high level at the 7th to the 21st day of postpartum,NEFA was highest at the 21st day of postpartum,the activity of alanine aminotransferase（ALT） and aspartate aminotransferase（AST） were highest at the 7th day of postpartum.This test proved that subclinical ketosis can occur at the 7th day of postpartum,and occur easily at the 21st day of postpartum.

关 键 词：奶牛 亚临床酮病 检测方法 生化指标 

分 类 号：S858.236.5[农业科学—临床兽医学]