子痫前期和正常妊娠代谢综合征变量的对比  

Comparison of metabolic syndrome variables among pregnant women with and without hypertensive disorder complicating pregnancy

作　　者：王妍平[1,2] 牛秀敏[1] 陈叙[2] 

机构地区：[1]天津医科大学总医院产科,天津300052 [2]天津市中心妇产科医院

出　　处：《现代妇产科进展》2010年第11期829-831,共3页Progress in Obstetrics and Gynecology

摘　　要：目的:研究妊娠期高血压疾病中代谢综合征变量的发生情况。方法:前瞻性对比年龄、孕周、产次相匹配的65例妊娠期高血压,60例子痫前期,30例子痫及33例正常妊娠孕妇的各项指标。主要测量指标包括血压、血脂、血糖及尿酸水平。结果:患者年龄19～40岁,平均28.5±4.6岁;妊娠期高血压,子痫前期和子痫患者的血压较对照组明显增加(收缩压P<0.01;舒张压P<0.01);子痫前期组和子痫组的血浆总胆固醇、甘油三酯、血糖和尿酸均明显高于妊娠期高血压组及对照组(P<0.05);妊娠期高血压组、子痫前期组及子痫组代谢综合征的发生率分别为13.8%、23.3%及26.7%。结论:妊娠期高血压疾病患者有代谢综合征的标志,推断两种情况相互关联。Objective：The aim of this study is to determine whether metabolic syndrome variables occur in gestational hypertension（GH）,preeclampsia and eclampsia.Methods：Consecutive 65 patients with GH,60 patients with preeclampsia and 30 patients with eclampsia were prospectively compared with age,gestational age and parity which matched 33 healthy pregnant women as a control group.The main outcome measures include blood pressure,plasma lipids,glucose and uric acid levels.Results：The patients were predominantly made up of primipara aged 28.5±4.6 years（19～40 years）.Patients with GH,preeclampsia and eclampsia had significantly higher blood pressure than the control（systolic blood pressure,P0.01;diastolic blood pressure,P0.01）.Compared with the control and GH group,preeclampsia and eclampsia groups also had significantly higher total plasma cholesterol,triglyceride,blood glucose and uric acid（P0.01）.The prevalence of this syndrome in the GH group,preeclampsia group and eclampsia group for the NCEP definitions was 13.8%,23.3% and 26.7% respectively.Conclusion：These results suggest that markers of metabolic syndrome and hypertensive disorder complicating pregnancy are positive linked.

关 键 词：妊娠期高血压疾病 代谢综合征 

分 类 号：R714.2[医药卫生—妇产科学]