不同照射时间下2450MHz微波辐射对小鼠脑内神经递质的影响  

Effects of 2450 MHz Microwave Irradiation of Different Duration on Central Transmitters in Mice.

作　　者：陈建[1] 杨玉华[1] 蒋睿[1] 浦京遂[1] 

机构地区：[1]航天医学工程研究所

出　　处：《航天医学与医学工程》1999年第3期220-222,共3页Space Medicine & Medical Engineering

摘　　要：目的探索微波辐射对中枢神经系统影响的机理。方法以２４５０ＭＨｚ微波理疗机为辐射源，在照射总剂量相同的条件下对ＬＡＣＡ纯种小白鼠分别进行２ｄ、７ｄ和１４ｄ照射，照射强度均为５ｍＷ／ｃｍ２。结果照射组小鼠大脑皮层的单胺氧化酶活性均较对照组高（Ｐ＜０．０５）；２ｄ、７ｄ组小鼠脑内去甲肾上腺素含量较对照组明显减少（Ｐ＜０．００１）；各照射组５羟吲哚乙酸含量均高于对照组，其中２ｄ和１４ｄ组显著升高（Ｐ＜０．００１）。Objective To investigate the mechanism of effects of microwave irradiation on central nervous system (CNS). Method 72 male LACA mice were irradiated with 2450 MHz microwave for 2,7 or 14 days respectively with the same total incident power density of 5 mW/cm2. Result After exposure, every group showed an increase of monoaminoxidase(MAO) in the cerebral cortex as compared with the control ( P <0.001 ). The norepinephrine(NE) content were significantly reduced after twoday or twoweek exposure( P <0. 05). The 5hydroxyindoleacetic acid (5HIAA) content, the main metabolite of 5hydroxytryptamine (5HT), were significantly increased after twoday or 7 day exposure ( P <0.001). ConclusionZ The metabolic abnormity of neurotransmitters in the central nervous system may be one of the factors causing disorders in the microwave operators.

关 键 词：微波辐射 中枢神经系统 神经递质 小鼠 

分 类 号：R594.8[医药卫生—内科学]