2005-2009年鲍氏不动杆菌检出及耐药率分析  

Detection Rate and Drug Resistance Rate of Acinetobacter baumanii during 2005-2009

作　　者：朱会英[1] 王艳[1] 褚亚辉[1] 徐德兴[1] 张海燕[1] 

机构地区：[1]广州军区广州总医院感染控制科,广东广州510010

出　　处：《中华医院感染学杂志》2010年第23期3778-3780,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析医院2005-2009年鲍氏不动杆菌检出及耐药性变迁规律,主要药物用量与耐药率变化之间的关系,为有效控制鲍氏不动杆菌感染率及耐药性不断上升的研究提供流行病学资料,也为临床医师用药提供指导。方法回顾性分析医院2005年1月-2009年12月临床送检标本中鲍氏不动杆菌检出率及耐药性,并对主要药物年用量进行统计。结果鲍氏不动杆菌2005-2009年分离率分别为:13.7%、12.6%、4.3%、9.2%、6.5%,对常用药物的耐药率呈逐年上升趋势。结论及时监控和掌握医院的鲍氏不动杆菌的耐药特点,是合理使用抗菌药物,努力控制和减少多药耐药鲍氏不动杆菌感染的关键。OBJECTIVE To analyze the change of the detection rate and drug resistance rate of Acinetobacter baumannii during 2005-2009,and the relationship between the change of dosage and the drug resistance rate,in order to provide epidemiologic data and directions for the clinicians to effectively control the increasing infection rate in A.baumannii and the drug resistance rate.METHODS The detection rate and drug resistant rate of A.baumanii of the clinical specimen submitted during Jan 2005-Dec 2009 were retrospectively analyzed.The dosage of the main antibiotics per year between 2005 and 2009 was collected and analyzed.RESULTS The detection rates of A.baumannii in five years were respectively as the followings： 13.7%,12.6%,4.3%,9.2% and 6.5%,the drug resistant rate to the common antibiotics kept an upward tendency.CONCLUSION Monitoring and grasping the drug resistance characteristics of A.baumannii are the key to the rational use of antibiotics,and to control and reduce the infection caused by multi-drug resistant A.baumannii.

关 键 词：鲍氏不动杆菌 耐药率 抗菌药物 用量 

分 类 号：R378[医药卫生—病原生物学]