2007～2009年北京、天津、广州三城市注射用抗菌药给药频度分析与合理性评价  

Analysis and Rationality Evaluation on the Administration Frequencies of Intravenous Antibiotics from 2007 to 2009 in Beijing, Tianjin and Guangzhou

作　　者：赵志刚[1] 王莉文[1] 巩红[2] 金岩[2] 

机构地区：[1]首都医科大学附属北京天坛医院药剂科,北京100050 [2]北京协和医院药剂科,北京100730

出　　处：《药品评价》2010年第20期30-33,共4页Drug Evaluation

摘　　要：目的: 研究2007～2009年北京、天津、广州三城市注射用抗菌药物给药频度及评价其合理性。方法: 统计2007～2009年北京、天津、广州地区注射用抗菌药物给药频度,并根据PK/PD特性进行合理性评价。结果: 氨基糖苷类、青霉素类、喹诺酮类、头孢菌素类和克林霉素给药频度见正文。结论: 青霉素类、喹头孢菌素类和克林霉素给药频度合理性较差,氨基糖苷类和喹诺酮类给药频度合理性较好。Objective： To investigate the administration frequencies of intravenous antibiotics from 2007 to 2009 in Beijing, Tianjin and Guangzhou and evaluate the rationality. Methods： Statistics were made on the administration frequencies of intravenous antibiotics from 2007 to 2009 in Beijing, Tianjin and Guangzhou and the rationality was evaluated by PK/PD characteristics. Results： The administration frequencies of aminoglycosides, penicillins, quinolones, cephalosporins and clindamycin are shown in the text. Conclusion： Administration frequencies of penicillins, cephalosporins and quinolones were not so rational, while administration frequencies of aminoglycosides and quinolones were basically rational.

关 键 词：PK/PD特性 给药频度 注射用抗菌药 合理性 

分 类 号：R96[医药卫生—药理学]