血液在体流动性无创测量方法及系统  

Non-invasive measurement of blood fluidity in vivo

作　　者：孙欣[1] 刘常春[1] 赵玉娟[1] 王新沛[1] 

机构地区：[1]山东大学控制科学与工程学院,山东济南250061

出　　处：《山东大学学报（工学版）》2010年第6期36-40,共5页Journal of Shandong University（Engineering Science）

基　　金：国家高技术研究发展计划(863计划)资助项目(2006AA02Z4D9)

摘　　要：血液流动性的降低是形成动脉粥样硬化进而导致心脑血管疾病的重要危险因素。血液流动性的定期跟踪检查对预防心脑血管疾病具有重要意义。建立了上肢血管系统的血液动力学模型,在分析血流阻断情况下动脉充盈压衰减过程的基础上,提出了血液在体流动性指数F,以表征人体的血液流动性,并阐述了其测量方法及测量系统。实验结果表明,本测量方法及测量系统具有很好的重复性、敏感性和特异性,对心血管疾病的早期预防具有较好的应用价值。Reduction of blood fluidity is an important risk factor for atherosclerosis and cardiovascular diseases. Frequent examination of blood fluidity has a great significance on prevention of cardiovascular diseases. A hemodynamic model of the vascular system of the upper limb was established. Based on the analysis of the decay of arterial static pressure, the blood fluidity index F was used to represent the blood fluidity in vivo. Using a function approximation method, the blood fluidity index F was calculated. Results of the experiment indicated that the method and the measurement system had good reproducibility and performed well in terms of sensitivity and specificity.

关 键 词：血液流动性 无创 在体 

分 类 号：R318.6[医药卫生—生物医学工程]