维吾尔语语义加工脑功能定位的磁共振成像研究  

Semantic judgment in Uygur character ： an fMRI study

作　　者：姜梅[1] 杨丽霞[1] 贾文霄[1] 亚热·艾拜都拉[2] 朱丽娜[1] 王红[1] 

机构地区：[1]新疆医科大学第二附属医院影像中心,乌鲁木齐830063 [2]新疆大学人文学院

出　　处：《中华神经外科杂志》2010年第11期1027-1030,共4页Chinese Journal of Neurosurgery

基　　金：国家自然科学基金资助项目（30760062）

摘　　要：目的 利用功能磁共振（fMRI）技术研究维吾尔族对其母语（维吾尔文字）进行词义联想脑功能的激活区及语言的偏侧化.方法 29例健康志愿者作为受试对象,通过视觉刺激对每个单音节实词进行词义联想同时行fMRI,所有数据经神经功能分析软件对相关脑皮质激活区进行个体分析及组分析.结果 多个皮质出现激活区,主要出现在双侧额中回、额下回、枕中回、中央前回及梭状回,左侧颞中回、顶上下小叶、楔前叶,右侧颞上回、舌回.左侧大脑半球激活体积明显大于右侧.结论 多个脑功能区参与维吾尔语义加工,fMRI能够很好地发现这些功能区,维吾尔族语言优势半球为左侧大脑半球.Objective To study the increasement of MRI signals in the functional cortical regions related to Uygur and functional lateralization using blood-oxygen dependent functional MRI （BOLD-fMRI ）technique.Method This study included 29 right-handed human volunteers,14 males and 15 females,aged from 18 to 28 years old.The functional images of brain were acquired with a PHILIPS Achieva nova dual 1.5 MRI.All data were analyzed on single-subject level and group level using SPM5.Results Several cortical and regions were activated.The activated areas included：bilateral middle/inferior frontal gyrus,precentral gyms and fusiform gyrus,right superior temporal gyrus,left middle temporal gyrus,left superior/inferiorparietal lobule,left precuneus,right lingual gyrus,bilateral occipital middle gyms.The activation volume in left hemisphere was larger than that in right hemisphere.Conclusions Many areas of cortex and subcortex are involved in Uygur character semantic judgment.fMRI is a good method to find these areas.Uygur task demonstrates left cerebral dominance.

关 键 词：维吾尔族 功能磁共振成像 语言 语义 

分 类 号：R686[医药卫生—骨科学]